Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3655166..3655826 Replicon chromosome
Accession NZ_CP119986
Organism Salmonella enterica strain CRIN514780

Toxin (Protein)


Gene name cptA Uniprot ID A0A5I5GR00
Locus tag P2V97_RS17790 Protein ID WP_000244761.1
Coordinates 3655166..3655579 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID S5MU13
Locus tag P2V97_RS17795 Protein ID WP_000351186.1
Coordinates 3655560..3655826 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P2V97_RS17770 (3651107) 3651107..3652840 - 1734 WP_000813387.1 single-stranded-DNA-specific exonuclease RecJ -
P2V97_RS17775 (3652846) 3652846..3653559 - 714 WP_000745614.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
P2V97_RS17780 (3653583) 3653583..3654479 - 897 WP_000434302.1 site-specific tyrosine recombinase XerD -
P2V97_RS17785 (3654592) 3654592..3655113 + 522 WP_001055885.1 flavodoxin FldB -
P2V97_RS17790 (3655166) 3655166..3655579 - 414 WP_000244761.1 protein YgfX Toxin
P2V97_RS17795 (3655560) 3655560..3655826 - 267 WP_000351186.1 FAD assembly factor SdhE Antitoxin
P2V97_RS17800 (3656076) 3656076..3657056 + 981 WP_023260866.1 tRNA-modifying protein YgfZ -
P2V97_RS17805 (3657172) 3657172..3657831 - 660 WP_000250289.1 hemolysin III family protein -
P2V97_RS17810 (3657995) 3657995..3658306 - 312 WP_001182976.1 N(4)-acetylcytidine aminohydrolase -
P2V97_RS17815 (3658464) 3658464..3659897 + 1434 WP_001230139.1 6-phospho-beta-glucosidase BglA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16199.15 Da        Isoelectric Point: 10.7537

>T274573 WP_000244761.1 NZ_CP119986:c3655579-3655166 [Salmonella enterica]
VVLWQSDLRVSWRAQWISLLIHGLVSAVILLMPWPLSYTPLWMILLSLVVFDCVRSQRRINTCQGEIKLLMDGRLRWQGQ
DWTLLRPPWLLKSGMVLRLRAESGRHQHLWLAADSMEEAEWRELRRILLQQPISGQH

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10550.05 Da        Isoelectric Point: 6.0783

>AT274573 WP_000351186.1 NZ_CP119986:c3655826-3655560 [Salmonella enterica]
MDIHNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFVRLLQSDDPDLFNWLMNHGKPADAELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A5I5GR00

Antitoxin

Source ID Structure
AlphaFold DB A0A5I0YWH4

References