Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2487173..2487316 Replicon chromosome
Accession NZ_CP119980
Organism Salmonella enterica strain CRIN525628

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2487175..2487278 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2487173..2487316 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P2V98_RS12055 2482303..2482503 + 201 Protein_2352 PagK family vesicle-borne virulence factor -
P2V98_RS12060 2482600..2483111 - 512 Protein_2353 tail fiber assembly protein -
P2V98_RS12065 2483124..2483411 - 288 Protein_2354 macro domain-containing protein -
P2V98_RS12070 2483421..2483636 - 216 Protein_2355 shikimate transporter -
P2V98_RS12075 2483638..2483898 - 261 Protein_2356 DUF1441 family protein -
P2V98_RS12080 2484206..2484373 + 168 WP_000789529.1 lytic enzyme -
P2V98_RS12085 2484630..2485163 - 534 WP_001050883.1 DUF2514 domain-containing protein -
P2V98_RS12090 2485217..2485408 - 192 Protein_2359 glycoside hydrolase family 19 protein -
P2V98_RS12095 2485397..2485858 + 462 Protein_2360 DNA breaking-rejoining protein -
P2V98_RS12100 2486122..2487015 + 894 Protein_2361 tyrosine-type recombinase/integrase -
- 2487173..2487316 + 144 - - Antitoxin
- 2487175..2487278 - 104 - - Toxin
P2V98_RS12105 2487418..2487771 - 354 WP_000722368.1 YebY family protein -
P2V98_RS12110 2487788..2488663 - 876 WP_000979694.1 copper homeostasis membrane protein CopD -
P2V98_RS12115 2488664..2489038 - 375 WP_000168393.1 CopC domain-containing protein YobA -
P2V98_RS12120 2489176..2489406 + 231 WP_000856224.1 DNA polymerase III subunit theta -
P2V98_RS12125 2489514..2490170 + 657 WP_000100256.1 nitrilase-related carbon-nitrogen hydrolase -
P2V98_RS12130 2490194..2490892 + 699 WP_000944278.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - sopE2 2467593..2492978 25385


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T274496 NZ_CP119980:c2487278-2487175 [Salmonella enterica]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 144 bp

>AT274496 NZ_CP119980:2487173-2487316 [Salmonella enterica]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References