Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2228819..2229090 Replicon chromosome
Accession NC_017641
Organism Escherichia coli UMNK88

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2228857..2228960 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2228819..2229090 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
UMNK88_RS11425 2225976..2227415 + 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
UMNK88_RS11430 2227533..2227769 + 237 WP_001295499.1 DUF1480 family protein -
UMNK88_RS11435 2227874..2228065 + 192 WP_001296140.1 YebW family protein -
UMNK88_RS11440 2228066..2228722 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 2228819..2229090 + 272 - - Antitoxin
- 2228857..2228960 - 104 - - Toxin
UMNK88_RS11450 2229117..2229458 - 342 WP_000976472.1 YebY family protein -
UMNK88_RS11455 2229471..2230343 - 873 WP_000879297.1 copper homeostasis membrane protein CopD -
UMNK88_RS11460 2230347..2230721 - 375 WP_000255065.1 CopC domain-containing protein YobA -
UMNK88_RS11465 2230860..2231090 + 231 WP_000916763.1 DNA polymerase III subunit theta -
UMNK88_RS11470 2231192..2231848 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
UMNK88_RS11475 2231872..2232534 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T27449 NC_017641:c2228960-2228857 [Escherichia coli UMNK88]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT27449 NC_017641:2228819-2229090 [Escherichia coli UMNK88]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTAGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References