Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | PP_4151-4152/excise(antitoxin) |
| Location | 1922163..1923202 | Replicon | chromosome |
| Accession | NZ_CP119967 | ||
| Organism | Pseudomonas sp. A34-9 | ||
Toxin (Protein)
| Gene name | PP_4152 | Uniprot ID | - |
| Locus tag | P3G59_RS08600 | Protein ID | WP_277761223.1 |
| Coordinates | 1922163..1922738 (-) | Length | 192 a.a. |
Antitoxin (Protein)
| Gene name | PP_4151 | Uniprot ID | - |
| Locus tag | P3G59_RS08605 | Protein ID | WP_277761224.1 |
| Coordinates | 1922735..1923202 (-) | Length | 156 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| P3G59_RS08575 | 1917488..1919476 | + | 1989 | WP_277761220.1 | heme lyase CcmF/NrfE family subunit | - |
| P3G59_RS08580 | 1919473..1920009 | + | 537 | WP_016987490.1 | DsbE family thiol:disulfide interchange protein | - |
| P3G59_RS08585 | 1920006..1920476 | + | 471 | WP_277761221.1 | cytochrome c-type biogenesis protein CcmH | - |
| P3G59_RS08590 | 1920473..1921675 | + | 1203 | WP_277761222.1 | c-type cytochrome biogenesis protein CcmI | - |
| P3G59_RS08595 | 1921701..1922105 | + | 405 | WP_158830025.1 | hypothetical protein | - |
| P3G59_RS08600 | 1922163..1922738 | - | 576 | WP_277761223.1 | PIN domain-containing protein | Toxin |
| P3G59_RS08605 | 1922735..1923202 | - | 468 | WP_277761224.1 | helix-turn-helix domain-containing protein | Antitoxin |
| P3G59_RS08610 | 1923377..1923484 | + | 108 | Protein_1697 | type II toxin-antitoxin system HicB family antitoxin | - |
| P3G59_RS08615 | 1923553..1924740 | - | 1188 | WP_277761225.1 | MFS transporter | - |
| P3G59_RS08620 | 1924984..1925604 | + | 621 | WP_277761226.1 | DUF5666 domain-containing protein | - |
| P3G59_RS08625 | 1925844..1926842 | - | 999 | WP_034151535.1 | sulfate ABC transporter substrate-binding protein | - |
| P3G59_RS08630 | 1927028..1927852 | - | 825 | WP_103306818.1 | ion transporter | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 192 a.a. Molecular weight: 21718.83 Da Isoelectric Point: 6.0065
>T274487 WP_277761223.1 NZ_CP119967:c1922738-1922163 [Pseudomonas sp. A34-9]
VRHSSFTAVYDACVLYPAPLRDFLMWLALSGRFRARWSKEIHSEWKRNLLKNRTDLTMEQLDRTSELMDRAIPEACVCDY
EELVNGLSLPDQDDRHVLAAAIRCGAGVIVTFNLKDFPDTQLAPFGIEAQHPDEFVENLFHLDSAAVVSAAQKQRKQLKT
PAMDVESFLRLLQRQGLTQSVQALEGYRAIL
VRHSSFTAVYDACVLYPAPLRDFLMWLALSGRFRARWSKEIHSEWKRNLLKNRTDLTMEQLDRTSELMDRAIPEACVCDY
EELVNGLSLPDQDDRHVLAAAIRCGAGVIVTFNLKDFPDTQLAPFGIEAQHPDEFVENLFHLDSAAVVSAAQKQRKQLKT
PAMDVESFLRLLQRQGLTQSVQALEGYRAIL
Download Length: 576 bp
Antitoxin
Download Length: 156 a.a. Molecular weight: 17297.72 Da Isoelectric Point: 6.1416
>AT274487 WP_277761224.1 NZ_CP119967:c1923202-1922735 [Pseudomonas sp. A34-9]
MSIITHSPINLPVEREVKAAIEGQRALAAYLATQFETQHIQIFDEQNEAHSIELPTSALRLLTDILAALAEGNAVKVVPI
HAELTTQEAADLLNVSRPHMIKLLESGEISYHKTGKHRRVRFADLMDYKTRRETASEQAMALLAEQAQALRTGYE
MSIITHSPINLPVEREVKAAIEGQRALAAYLATQFETQHIQIFDEQNEAHSIELPTSALRLLTDILAALAEGNAVKVVPI
HAELTTQEAADLLNVSRPHMIKLLESGEISYHKTGKHRRVRFADLMDYKTRRETASEQAMALLAEQAQALRTGYE
Download Length: 468 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|