Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yfjZ-ypjF/CbtA-CbeA
Location 1126552..1127209 Replicon chromosome
Accession NZ_CP119862
Organism Citrobacter sp. S171

Toxin (Protein)


Gene name ypjF Uniprot ID -
Locus tag P2W74_RS05415 Protein ID WP_276294209.1
Coordinates 1126552..1126872 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag P2W74_RS05420 Protein ID WP_276294210.1
Coordinates 1126892..1127209 (-) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P2W74_RS05405 (1123451) 1123451..1124656 - 1206 WP_276294208.1 DUF4236 domain-containing protein -
P2W74_RS05410 (1124841) 1124841..1126216 - 1376 Protein_1057 IS3 family transposase -
P2W74_RS05415 (1126552) 1126552..1126872 - 321 WP_276294209.1 TA system toxin CbtA family protein Toxin
P2W74_RS05420 (1126892) 1126892..1127209 - 318 WP_276294210.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
P2W74_RS05425 (1127227) 1127227..1127448 - 222 WP_276294211.1 DUF987 domain-containing protein -
P2W74_RS05430 (1127457) 1127457..1127933 - 477 WP_276294212.1 RadC family protein -
P2W74_RS05435 (1127949) 1127949..1128407 - 459 WP_276294213.1 antirestriction protein -
P2W74_RS05440 (1128508) 1128508..1128747 - 240 WP_276294214.1 DUF905 domain-containing protein -
P2W74_RS05445 (1128847) 1128847..1129755 - 909 WP_276294215.1 Ivy family c-type lysozyme inhibitor -
P2W74_RS05450 (1129824) 1129824..1129991 - 168 Protein_1065 DUF4339 domain-containing protein -
P2W74_RS05455 (1130029) 1130029..1130724 - 696 WP_276294216.1 transcriptional regulator -
P2W74_RS05460 (1130951) 1130951..1131778 - 828 WP_276294217.1 DUF932 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1123451..1179809 56358
- flank IS/Tn - - 1124841..1125071 230


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-100)

Antitoxin

Antitoxin CbeA

(5-104)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12220.16 Da        Isoelectric Point: 8.0375

>T274463 WP_276294209.1 NZ_CP119862:c1126872-1126552 [Citrobacter sp. S171]
MKTLPATISRAAKPCLSPVAVWQMLLTRLLEQHYGLTLNDTPFSDETVIKEHIDASISLVDAVNFLVEKYELVRIDRKGF
SWQEQSPFITTVDILRARRTMRETRT

Download         Length: 321 bp

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11993.64 Da        Isoelectric Point: 6.9464

>AT274463 WP_276294210.1 NZ_CP119862:c1127209-1126892 [Citrobacter sp. S171]
MSNTTWGLQRDITQRLGARLVQEGNRLHYLADRASIIGKFSDAECRKLDETFPHFISQMELMLITGELNPRHAHCVNLYH
NGFTCEADTLGSCGYVYIAVYLTQR

Download         Length: 318 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References