Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 807444..808104 Replicon chromosome
Accession NZ_CP119862
Organism Citrobacter sp. S171

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag P2W74_RS03965 Protein ID WP_276293976.1
Coordinates 807691..808104 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag P2W74_RS03960 Protein ID WP_162380161.1
Coordinates 807444..807710 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P2W74_RS03935 (802645) 802645..804078 - 1434 WP_276293973.1 6-phospho-beta-glucosidase BglA -
P2W74_RS03940 (804199) 804199..804927 - 729 WP_276295123.1 MurR/RpiR family transcriptional regulator -
P2W74_RS03945 (804980) 804980..805291 + 312 WP_276295124.1 N(4)-acetylcytidine aminohydrolase -
P2W74_RS03950 (805454) 805454..806113 + 660 WP_276293974.1 hemolysin III family protein -
P2W74_RS03955 (806207) 806207..807187 - 981 WP_276293975.1 tRNA-modifying protein YgfZ -
P2W74_RS03960 (807444) 807444..807710 + 267 WP_162380161.1 FAD assembly factor SdhE Antitoxin
P2W74_RS03965 (807691) 807691..808104 + 414 WP_276293976.1 protein YgfX Toxin
P2W74_RS03970 (808172) 808172..808693 - 522 WP_276293977.1 flavodoxin FldB -
P2W74_RS03975 (808806) 808806..809702 + 897 WP_276293978.1 site-specific tyrosine recombinase XerD -
P2W74_RS03980 (809726) 809726..810439 + 714 WP_276293979.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
P2W74_RS03985 (810445) 810445..812178 + 1734 WP_276293980.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16389.43 Da        Isoelectric Point: 11.0586

>T274462 WP_276293976.1 NZ_CP119862:807691-808104 [Citrobacter sp. S171]
VVLWQSDLRVSWRAQWLSLLLHGLVAALILLMPWPLSYTPLWLILLSLVVFDCVRSQRRINTRQGEIKLLMDGRLRWQGL
EWAILSAPWMLKTGMMMRLRSDSGRRQHLWLAADSMDEKEWRELRRVMLQQTEQEKH

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10544.06 Da        Isoelectric Point: 5.1599

>AT274462 WP_162380161.1 NZ_CP119862:807444-807710 [Citrobacter sp. S171]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDDEKRIFIRLLECDDPDLFNWLMNHGKPADAELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References