Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/Doc-RelB
Location 4469322..4469917 Replicon chromosome
Accession NZ_CP119773
Organism Dickeya fangzhongdai strain ZXC1

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag PQ617_RS19805 Protein ID WP_038658062.1
Coordinates 4469322..4469699 (-) Length 126 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag PQ617_RS19810 Protein ID WP_039692075.1
Coordinates 4469696..4469917 (-) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PQ617_RS19785 (PQ617_19785) 4465425..4465655 + 231 WP_107759568.1 tautomerase PptA -
PQ617_RS19790 (PQ617_19790) 4466154..4467131 + 978 WP_049854088.1 DUF1852 domain-containing protein -
PQ617_RS19795 (PQ617_19795) 4467159..4468190 + 1032 WP_276217993.1 methionine synthase -
PQ617_RS19800 (PQ617_19800) 4468378..4469025 - 648 WP_276217995.1 EcsC family protein -
PQ617_RS19805 (PQ617_19805) 4469322..4469699 - 378 WP_038658062.1 type II toxin-antitoxin system death-on-curing family toxin Toxin
PQ617_RS19810 (PQ617_19810) 4469696..4469917 - 222 WP_039692075.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PQ617_RS19815 (PQ617_19815) 4470054..4471202 - 1149 WP_276217997.1 L-threonine dehydrogenase -
PQ617_RS19820 (PQ617_19820) 4471589..4472044 + 456 WP_238556038.1 NUDIX domain-containing protein -
PQ617_RS19830 (PQ617_19830) 4472889..4473566 - 678 WP_038658056.1 respiratory nitrate reductase subunit gamma -
PQ617_RS19835 (PQ617_19835) 4473566..4474285 - 720 WP_276217999.1 nitrate reductase molybdenum cofactor assembly chaperone -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Fido domain

(4-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-52)


Sequences

Toxin        


Download         Length: 126 a.a.        Molecular weight: 14194.26 Da        Isoelectric Point: 5.1873

>T274460 WP_038658062.1 NZ_CP119773:c4469699-4469322 [Dickeya fangzhongdai]
MKWVSAQDVIAFHDRILQVLPGVAGMADPGRAEALIYRVQNRLYYEDMTDLFELAATYWVTVARGHIFNDGNKRTAFFVT
MVFLRRNGVLIADNDNSLEELTVKAATGECQVSELAEQLRLRVEK

Download         Length: 378 bp

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8190.26 Da        Isoelectric Point: 7.2021

>AT274460 WP_039692075.1 NZ_CP119773:c4469917-4469696 [Dickeya fangzhongdai]
MKTYTITEARQNIAAVIDTAARGEPVEITRRNGTSAVLIPKAEFEAYQNARLDAEFDFIMQRHGHTVKALADR

Download         Length: 222 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References