274455

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DhiAT/dnstrm_HI1420(antitoxin)
Location 3363960..3364713 Replicon chromosome
Accession NZ_CP119773
Organism Dickeya fangzhongdai strain ZXC1

Toxin (Protein)


Gene name dhiT Uniprot ID A0A2K8QMG8
Locus tag PQ617_RS14925 Protein ID WP_038918519.1
Coordinates 3363960..3364217 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name dhiA Uniprot ID A0A2K8QKC0
Locus tag PQ617_RS14930 Protein ID WP_038918520.1
Coordinates 3364225..3364713 (+) Length 163 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PQ617_RS14915 (PQ617_14915) 3360735..3362885 - 2151 WP_276196184.1 formate dehydrogenase subunit alpha -
PQ617_RS14920 (PQ617_14920) 3362920..3363462 - 543 WP_013317225.1 4Fe-4S dicluster domain-containing protein -
PQ617_RS14925 (PQ617_14925) 3363960..3364217 + 258 WP_038918519.1 DUF4160 domain-containing protein Toxin
PQ617_RS14930 (PQ617_14930) 3364225..3364713 + 489 WP_038918520.1 addiction module antitoxin Antitoxin
PQ617_RS14935 (PQ617_14935) 3364798..3365295 - 498 WP_038918521.1 hydrogenase maturation peptidase HycI -
PQ617_RS14940 (PQ617_14940) 3365288..3365686 - 399 WP_276196185.1 formate hydrogenlyase maturation HycH family protein -
PQ617_RS14945 (PQ617_14945) 3365683..3366474 - 792 WP_276196186.1 NADH-quinone oxidoreductase subunit B family protein -
PQ617_RS14950 (PQ617_14950) 3366471..3367040 - 570 WP_039691199.1 hydrogenase 4 subunit H -
PQ617_RS14955 (PQ617_14955) 3367051..3368778 - 1728 WP_276196187.1 hydrogenase large subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Protein of unknown function DUF4160

(9-74)

Antitoxin

Uncharacterized protein HI1420

(79-157)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9977.52 Da        Isoelectric Point: 8.1489

>T274455 WP_038918519.1 NZ_CP119773:3363960-3364217 [Dickeya fangzhongdai]
MPEIDRLAGLIFHLYFYDDERHHLPHVHVCYGNHELIISIRTGTEIEGYLPNNKRKLALAHIRAHREQLLSMWERAVVGR
NPGKL

Download         Length: 258 bp

Antitoxin


Download         Length: 163 a.a.        Molecular weight: 17940.51 Da        Isoelectric Point: 6.9795

>AT274455 WP_038918520.1 NZ_CP119773:3364225-3364713 [Dickeya fangzhongdai]
MHKIVEVDVIGDFSLRLTYEDGLVCDINLYQYASSPVFSNASLFIKFGLLPDGSLEWSPDIKISASELRKKGEYVSHTLA
VREKNFADVISRAFYDAVIENRPEILQAALKIAVEKHGNSTVAKEAGAKSRTSLYKSLNKNTHVSLATVVSLAHTVLQLE
EK

Download         Length: 489 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2K8QMG8

Antitoxin

Source ID Structure
AlphaFold DB A0A2K8QKC0

References