Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 3308067..3308620 Replicon chromosome
Accession NZ_CP119773
Organism Dickeya fangzhongdai strain ZXC1

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag PQ617_RS14685 Protein ID WP_276196150.1
Coordinates 3308306..3308620 (+) Length 105 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag PQ617_RS14680 Protein ID WP_110372302.1
Coordinates 3308067..3308303 (+) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PQ617_RS14665 (PQ617_14665) 3303612..3304847 - 1236 WP_276196149.1 DNA cytosine methyltransferase -
PQ617_RS14670 (PQ617_14670) 3305128..3306150 + 1023 WP_210182511.1 DUF4917 family protein -
PQ617_RS14675 (PQ617_14675) 3306802..3307743 + 942 Protein_2846 zincin-like metallopeptidase domain-containing protein -
PQ617_RS14680 (PQ617_14680) 3308067..3308303 + 237 WP_110372302.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
PQ617_RS14685 (PQ617_14685) 3308306..3308620 + 315 WP_276196150.1 CcdB family protein Toxin
PQ617_RS14690 (PQ617_14690) 3308623..3309372 + 750 WP_276196151.1 hypothetical protein -
PQ617_RS14695 (PQ617_14695) 3309586..3310437 - 852 WP_276196153.1 hypothetical protein -
PQ617_RS14700 (PQ617_14700) 3310431..3312185 - 1755 WP_276196154.1 ATP-binding protein -
PQ617_RS14705 (PQ617_14705) 3312656..3313393 + 738 WP_276196155.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3284322..3315999 31677


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-103)

Antitoxin

Post-segregation antitoxin CcdA

(9-78)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11519.49 Da        Isoelectric Point: 6.9727

>T274454 WP_276196150.1 NZ_CP119773:3308306-3308620 [Dickeya fangzhongdai]
MQFTVYGNTGKSTVYPLLLDVTSDIIGQLNRRIVIPLLPIEKYPAGRRPDRLVPVVMLTDGKEYAVMTHELASIPVQVLG
AVFCDASQYRNQVKAAIDFLIDGI

Download         Length: 315 bp

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 9031.05 Da        Isoelectric Point: 6.4792

>AT274454 WP_110372302.1 NZ_CP119773:3308067-3308303 [Dickeya fangzhongdai]
MTAKQRNTQSVTMTVERALLVRAREAGINLSATLTTALDAELRHHEAKKWQEENREAIDALNRFHDEHGCFSDEYRTF

Download         Length: 237 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References