Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 2602789..2603315 Replicon chromosome
Accession NZ_CP119773
Organism Dickeya fangzhongdai strain ZXC1

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag PQ617_RS11670 Protein ID WP_276195650.1
Coordinates 2602789..2603094 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag PQ617_RS11675 Protein ID WP_276195651.1
Coordinates 2603097..2603315 (-) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PQ617_RS11650 (PQ617_11650) 2598092..2598898 + 807 WP_276195645.1 oxidoreductase -
PQ617_RS11655 (PQ617_11655) 2599137..2599309 + 173 Protein_2256 GNAT family N-acetyltransferase -
PQ617_RS11660 (PQ617_11660) 2599383..2600494 + 1112 WP_276195647.1 IS3 family transposase -
PQ617_RS11665 (PQ617_11665) 2601167..2602399 - 1233 WP_276195649.1 hypothetical protein -
PQ617_RS11670 (PQ617_11670) 2602789..2603094 - 306 WP_276195650.1 type II toxin-antitoxin system toxin CcdB Toxin
PQ617_RS11675 (PQ617_11675) 2603097..2603315 - 219 WP_276195651.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin
PQ617_RS11680 (PQ617_11680) 2603374..2604117 - 744 WP_276195652.1 MobC family replication-relaxation protein -
PQ617_RS11685 (PQ617_11685) 2605020..2605370 - 351 WP_276195653.1 hypothetical protein -
PQ617_RS11690 (PQ617_11690) 2605557..2605751 + 195 WP_019844359.1 YlcI/YnfO family protein -
PQ617_RS11695 (PQ617_11695) 2605857..2607116 - 1260 WP_276195654.1 integrase arm-type DNA-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2584944..2604853 19909


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-100)

Antitoxin

Post-segregation antitoxin CcdA

(2-72)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11731.64 Da        Isoelectric Point: 4.8500

>T274451 WP_276195650.1 NZ_CP119773:c2603094-2602789 [Dickeya fangzhongdai]
MQFIVYQYKRASHYKMFVDVQSDIVETPKRRMVIPLIESHHLSEKVNKTLFPLLRIDGEDYRLMTTELSSVPVEVIGEVI
ADLSDCADEIKDAINLMFWGI

Download         Length: 306 bp

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8259.20 Da        Isoelectric Point: 7.2041

>AT274451 WP_276195651.1 NZ_CP119773:c2603315-2603097 [Dickeya fangzhongdai]
MKHRVSVTVDKDNYQVLSAAGVNISGLVNDAIGKEARRIRTEEWKKENREGMEEVARFIAQHGSFADENRNW

Download         Length: 219 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References