Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 2306033..2306711 Replicon chromosome
Accession NZ_CP119773
Organism Dickeya fangzhongdai strain ZXC1

Toxin (Protein)


Gene name cptA Uniprot ID A0A2K8QJH4
Locus tag PQ617_RS10480 Protein ID WP_049854564.1
Coordinates 2306280..2306711 (+) Length 144 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A2K8QSU7
Locus tag PQ617_RS10475 Protein ID WP_023637600.1
Coordinates 2306033..2306299 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PQ617_RS10455 (PQ617_10455) 2302480..2303130 + 651 WP_038917839.1 LysE family translocator -
PQ617_RS10460 (PQ617_10460) 2303201..2303809 - 609 WP_276219452.1 HD domain-containing protein -
PQ617_RS10465 (PQ617_10465) 2304020..2304670 + 651 WP_038917842.1 hemolysin III family protein -
PQ617_RS10470 (PQ617_10470) 2304743..2305723 - 981 WP_276219453.1 tRNA-modifying protein YgfZ -
PQ617_RS10475 (PQ617_10475) 2306033..2306299 + 267 WP_023637600.1 FAD assembly factor SdhE Antitoxin
PQ617_RS10480 (PQ617_10480) 2306280..2306711 + 432 WP_049854564.1 protein YgfX Toxin
PQ617_RS10485 (PQ617_10485) 2306811..2307329 - 519 WP_107758698.1 flavodoxin FldB -
PQ617_RS10490 (PQ617_10490) 2307458..2308783 - 1326 WP_276219454.1 MFS transporter -
PQ617_RS10495 (PQ617_10495) 2309046..2309945 + 900 WP_038917846.1 site-specific tyrosine recombinase XerD -
PQ617_RS10500 (PQ617_10500) 2310034..2310750 + 717 WP_038917847.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 144 a.a.        Molecular weight: 16793.54 Da        Isoelectric Point: 11.7737

>T274450 WP_049854564.1 NZ_CP119773:2306280-2306711 [Dickeya fangzhongdai]
VAQWQCDLRVSWRMQLFSLLTHGFLVLMILLAPWPDGYAPLWLGLVTLVVFGFVRSQRIIKSRQGEISLHGENQLHWQQR
DWQIARRPWVMRNGVLLSLRATTGKGHQRLWLASDSMGNEEWRLLRQLLLQHPLQGTESSRHH

Download         Length: 432 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10544.03 Da        Isoelectric Point: 5.5535

>AT274450 WP_023637600.1 NZ_CP119773:2306033-2306299 [Dickeya fangzhongdai]
MDINNKSRIHWACRRGMRELDISIMPFFEHEYDTLSDDDKQHFIRLLQCDDPDLFNWLMNHGEPVDPELKRMVSLIQTRN
KDRGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2K8QJH4

Antitoxin

Source ID Structure
AlphaFold DB A0A2K8QSU7

References