Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 2176424..2176950 Replicon chromosome
Accession NZ_CP119773
Organism Dickeya fangzhongdai strain ZXC1

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag PQ617_RS09855 Protein ID WP_276219395.1
Coordinates 2176424..2176729 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag PQ617_RS09860 Protein ID WP_039534392.1
Coordinates 2176732..2176950 (-) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PQ617_RS09845 (PQ617_09845) 2171644..2174277 - 2634 WP_276219393.1 DEAD/DEAH box helicase family protein -
PQ617_RS09850 (PQ617_09850) 2174268..2175995 - 1728 WP_276219394.1 site-specific DNA-methyltransferase -
PQ617_RS09855 (PQ617_09855) 2176424..2176729 - 306 WP_276219395.1 type II toxin-antitoxin system toxin CcdB Toxin
PQ617_RS09860 (PQ617_09860) 2176732..2176950 - 219 WP_039534392.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin
PQ617_RS09865 (PQ617_09865) 2177009..2177752 - 744 WP_276219397.1 MobC family replication-relaxation protein -
PQ617_RS09870 (PQ617_09870) 2178664..2179005 - 342 WP_276219399.1 hypothetical protein -
PQ617_RS09875 (PQ617_09875) 2179146..2179316 + 171 WP_162847981.1 hypothetical protein -
PQ617_RS09880 (PQ617_09880) 2179457..2180716 - 1260 WP_276219401.1 integrase arm-type DNA-binding domain-containing protein -
PQ617_RS09890 (PQ617_09890) 2181116..2181691 - 576 WP_276219632.1 transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 2163753..2180716 16963
- flank IS/Tn - - 2170350..2171558 1208


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-100)

Antitoxin

Post-segregation antitoxin CcdA

(2-72)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11753.58 Da        Isoelectric Point: 4.8500

>T274449 WP_276219395.1 NZ_CP119773:c2176729-2176424 [Dickeya fangzhongdai]
MQFIVYQYKRASHYKMFVDVQSDIVETPKRRMVIPIIEAHHLSEKVNKTLFPLIRIDSEDYRLMTTELSSVSVEVIGEVT
ADLGDYADEIKDAINLMFWGI

Download         Length: 306 bp

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8243.20 Da        Isoelectric Point: 7.2043

>AT274449 WP_039534392.1 NZ_CP119773:c2176950-2176732 [Dickeya fangzhongdai]
MKHRVSVTVDKDNYQVLSAAGVNISGLVNEAIGKEARRIRAEEWKKENREGMEEVARFIAQHGSFADENRNW

Download         Length: 219 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References