Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | PP_4151-4152/excise(antitoxin) |
| Location | 1984964..1986000 | Replicon | chromosome |
| Accession | NZ_CP119773 | ||
| Organism | Dickeya fangzhongdai strain ZXC1 | ||
Toxin (Protein)
| Gene name | PP_4152 | Uniprot ID | - |
| Locus tag | PQ617_RS08980 | Protein ID | WP_049855243.1 |
| Coordinates | 1985425..1986000 (+) | Length | 192 a.a. |
Antitoxin (Protein)
| Gene name | PP_4151 | Uniprot ID | - |
| Locus tag | PQ617_RS08975 | Protein ID | WP_038917616.1 |
| Coordinates | 1984964..1985425 (+) | Length | 154 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PQ617_RS08955 (PQ617_08955) | 1980085..1980732 | + | 648 | WP_049855240.1 | type I-E CRISPR-associated protein Cas6/Cse3/CasE | - |
| PQ617_RS08960 (PQ617_08960) | 1980746..1981669 | + | 924 | WP_276219263.1 | type I-E CRISPR-associated endonuclease Cas1e | - |
| PQ617_RS08965 (PQ617_08965) | 1981666..1981959 | + | 294 | WP_038917614.1 | type I-E CRISPR-associated endoribonuclease Cas2e | - |
| PQ617_RS08970 (PQ617_08970) | 1982743..1984419 | - | 1677 | WP_276219265.1 | methyl-accepting chemotaxis protein | - |
| PQ617_RS08975 (PQ617_08975) | 1984964..1985425 | + | 462 | WP_038917616.1 | helix-turn-helix domain-containing protein | Antitoxin |
| PQ617_RS08980 (PQ617_08980) | 1985425..1986000 | + | 576 | WP_049855243.1 | PIN domain-containing protein | Toxin |
| PQ617_RS08985 (PQ617_08985) | 1986224..1986676 | + | 453 | WP_276219267.1 | YhbP family protein | - |
| PQ617_RS08990 (PQ617_08990) | 1986787..1987251 | - | 465 | WP_038917620.1 | anaerobic ribonucleoside-triphosphate reductase-activating protein | - |
| PQ617_RS08995 (PQ617_08995) | 1987350..1989488 | - | 2139 | WP_100848752.1 | anaerobic ribonucleoside-triphosphate reductase | - |
| PQ617_RS09000 (PQ617_09000) | 1989868..1990776 | + | 909 | WP_276219269.1 | homocysteine S-methyltransferase family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 192 a.a. Molecular weight: 21659.95 Da Isoelectric Point: 4.8531
>T274446 WP_049855243.1 NZ_CP119773:1985425-1986000 [Dickeya fangzhongdai]
MTHTPYPVVLDACVIYPSLLRDLLIHLGLTGLYQPKWTAIIEDEWQRNLLLNRPDLTPEQISRTRELMNQAIPDAMITGF
EALIPGITLPDPDDQHVVAAAIRSNAEIIVTFNLKDFPHPEIDNFGIEALHPDDFITDLLDLNQALVLSAVSRQRHSMRK
PPKSVDEYLDALLRQSLPQTVKELSKFHTLI
MTHTPYPVVLDACVIYPSLLRDLLIHLGLTGLYQPKWTAIIEDEWQRNLLLNRPDLTPEQISRTRELMNQAIPDAMITGF
EALIPGITLPDPDDQHVVAAAIRSNAEIIVTFNLKDFPHPEIDNFGIEALHPDDFITDLLDLNQALVLSAVSRQRHSMRK
PPKSVDEYLDALLRQSLPQTVKELSKFHTLI
Download Length: 576 bp
Antitoxin
Download Length: 154 a.a. Molecular weight: 16913.27 Da Isoelectric Point: 6.2221
>AT274446 WP_038917616.1 NZ_CP119773:1984964-1985425 [Dickeya fangzhongdai]
MTNSILDSLSLPAPGEIEAAVRGQRELAAYLSTKMETQKISIQDADNNTRQVELPTSALTLLMSILGELAVGNAVQVVPV
HAELTTQEAANILNVSRPHMVKLLEDGKLPFHKTGRHRRVLFADLMDYKHQRDNESSRAMQALADHSQELGLY
MTNSILDSLSLPAPGEIEAAVRGQRELAAYLSTKMETQKISIQDADNNTRQVELPTSALTLLMSILGELAVGNAVQVVPV
HAELTTQEAANILNVSRPHMVKLLEDGKLPFHKTGRHRRVLFADLMDYKHQRDNESSRAMQALADHSQELGLY
Download Length: 462 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|