Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1(toxin)
Location 4763860..4764482 Replicon chromosome
Accession NZ_CP119754
Organism Superficieibacter sp. HKU1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag P0H77_RS22650 Protein ID WP_276160102.1
Coordinates 4763860..4764231 (-) Length 124 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag P0H77_RS22655 Protein ID WP_276160106.1
Coordinates 4764228..4764482 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P0H77_RS22635 (P0H77_22640) 4761356..4762258 + 903 WP_176919603.1 formate dehydrogenase subunit beta -
P0H77_RS22640 (P0H77_22645) 4762255..4762890 + 636 WP_276160093.1 formate dehydrogenase cytochrome b556 subunit -
P0H77_RS22645 (P0H77_22650) 4762887..4763816 + 930 WP_276160096.1 formate dehydrogenase accessory protein FdhE -
P0H77_RS22650 (P0H77_22655) 4763860..4764231 - 372 WP_276160102.1 type II toxin-antitoxin system VapC family toxin Toxin
P0H77_RS22655 (P0H77_22660) 4764228..4764482 - 255 WP_276160106.1 CopG family transcriptional regulator Antitoxin
P0H77_RS22660 (P0H77_22665) 4765149..4765691 - 543 WP_276160108.1 shikimate kinase -
P0H77_RS22665 (P0H77_22670) 4765881..4766045 + 165 WP_276160109.1 hypothetical protein -
P0H77_RS22670 (P0H77_22675) 4767297..4768658 + 1362 WP_276160110.1 glycosyltransferase family 2 protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(6-111)

Antitoxin

Ribbon-helix-helix protein, CopG

(15-49)


Sequences

Toxin        


Download         Length: 124 a.a.        Molecular weight: 13912.11 Da        Isoelectric Point: 9.4615

>T274437 WP_276160102.1 NZ_CP119754:c4764231-4763860 [Superficieibacter sp. HKU1]
MKGKALFDTNILIDLFNGHREAMSALEAYPPQHAISLVTWMEVMVGAKKYHREHQTRMALSAFNIIGISQDIAERSVNLR
QEFGLKLPDAIILATAQHHRYTMVTRNTKDFAGIPGVVTPYQF

Download         Length: 372 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9725.01 Da        Isoelectric Point: 4.3805

>AT274437 WP_276160106.1 NZ_CP119754:c4764482-4764228 [Superficieibacter sp. HKU1]
MSMVAGIDMGRILLDLSDDVIKRLDDLKHQRGLPRAELLREAVEEYLERQNQAKAAIANALGLWQGFEEDGVEFERALRE
EWER

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References