Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 81705..82423 Replicon chromosome
Accession NZ_CP119754
Organism Superficieibacter sp. HKU1

Toxin (Protein)


Gene name yeeV Uniprot ID A0A822WUK4
Locus tag P0H77_RS00405 Protein ID WP_071605960.1
Coordinates 81705..82025 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID A0A822X2D3
Locus tag P0H77_RS00410 Protein ID WP_054627869.1
Coordinates 82067..82423 (-) Length 119 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P0H77_RS00380 (P0H77_00380) 77655..77942 - 288 WP_276160739.1 SymE family type I addiction module toxin -
P0H77_RS00385 (P0H77_00385) 78080..78268 + 189 WP_276160746.1 toxin-antitoxin system HicB family antitoxin -
P0H77_RS00390 (P0H77_00390) 78456..79490 - 1035 WP_276160749.1 CHAT domain-containing protein -
P0H77_RS00395 (P0H77_00395) 79761..80180 - 420 WP_276160753.1 toll/interleukin-1 receptor domain-containing protein -
P0H77_RS00400 (P0H77_00400) 80867..81214 + 348 WP_276160755.1 DUF6404 family protein -
P0H77_RS00405 (P0H77_00405) 81705..82025 - 321 WP_071605960.1 TA system toxin CbtA family protein Toxin
P0H77_RS00410 (P0H77_00410) 82067..82423 - 357 WP_054627869.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
P0H77_RS00415 (P0H77_00415) 82455..82676 - 222 WP_054627868.1 DUF987 family protein -
P0H77_RS00420 (P0H77_00420) 82685..83155 - 471 WP_276160779.1 DNA repair protein RadC -
P0H77_RS00425 (P0H77_00425) 83225..84046 - 822 WP_044599778.1 DUF932 domain-containing protein -
P0H77_RS00430 (P0H77_00430) 84739..85578 - 840 WP_137574673.1 hypothetical protein -
P0H77_RS00435 (P0H77_00435) 85638..86072 - 435 WP_054627865.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(5-104)

Antitoxin

Antitoxin CbeA

(18-117)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12227.83 Da        Isoelectric Point: 6.3229

>T274423 WP_071605960.1 NZ_CP119754:c82025-81705 [Superficieibacter sp. HKU1]
MHISTVPKTVTVSSRLSPVQVWQKLLTYILEHHYGLTINDTPFSNDTTIQEHIEAGVNLTDAVNFLVERFELVRIDQKSF
SWQDQEPWITSLDVHRAQSNLGLKRP

Download         Length: 321 bp

Antitoxin


Download         Length: 119 a.a.        Molecular weight: 13069.72 Da        Isoelectric Point: 5.9473

>AT274423 WP_054627869.1 NZ_CP119754:c82423-82067 [Superficieibacter sp. HKU1]
MQSTTISGTSAENTSCLQWGLKRNITPCFGARLVQEGNRIYFLADRAGFNGSFSDAEALSLDQAFPLMVKQLERMLTTGE
LDPHNQHCVTLHHNGLTCEADTLGSYGYVYIAIYPHQL

Download         Length: 357 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A822WUK4

Antitoxin

Source ID Structure
AlphaFold DB A0A822X2D3

References