Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 1144789..1145441 Replicon chromosome
Accession NZ_CP119753
Organism Microbacter sp. GSS18

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag P0L94_RS05430 Protein ID WP_276179984.1
Coordinates 1144789..1145178 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag P0L94_RS05435 Protein ID WP_276179986.1
Coordinates 1145187..1145441 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P0L94_RS05405 (P0L94_05405) 1139868..1140845 + 978 WP_276179974.1 cysteine synthase family protein -
P0L94_RS05410 (P0L94_05410) 1140887..1141633 + 747 WP_276179976.1 SUMF1/EgtB/PvdO family nonheme iron enzyme -
P0L94_RS05415 (P0L94_05415) 1141713..1142090 + 378 WP_276179978.1 metalloregulator ArsR/SmtB family transcription factor -
P0L94_RS05420 (P0L94_05420) 1142087..1143757 + 1671 WP_276179980.1 SulP family inorganic anion transporter -
P0L94_RS05425 (P0L94_05425) 1143868..1144626 + 759 WP_276179982.1 MBL fold metallo-hydrolase -
P0L94_RS05430 (P0L94_05430) 1144789..1145178 - 390 WP_276179984.1 type II toxin-antitoxin system VapC family toxin Toxin
P0L94_RS05435 (P0L94_05435) 1145187..1145441 - 255 WP_276179986.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
P0L94_RS05440 (P0L94_05440) 1145532..1146452 + 921 WP_276179987.1 AEC family transporter -
P0L94_RS05445 (P0L94_05445) 1146620..1147177 + 558 WP_276179989.1 DUF308 domain-containing protein -
P0L94_RS05450 (P0L94_05450) 1147232..1149223 - 1992 WP_276179991.1 S9 family peptidase -
P0L94_RS05455 (P0L94_05455) 1149226..1149990 - 765 WP_276179993.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin

Antitoxin VapB-like

(1-83)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 13434.04 Da        Isoelectric Point: 5.1029

>T274422 WP_276179984.1 NZ_CP119753:c1145178-1144789 [Microbacter sp. GSS18]
VADTSALVAVVFGEADARAFASVLAAHAGDVSVSAATLVEARIVVEGRQGTEAAADLDRLLTRLGAHVVAVDDAQASLAT
SAWRRFGKGRHDAGLNFGDCFSYALSKHLDVPLLYKGDDFSRTDVASAM

Download         Length: 390 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9164.22 Da        Isoelectric Point: 4.5642

>AT274422 WP_276179986.1 NZ_CP119753:c1145441-1145187 [Microbacter sp. GSS18]
MALNIKDPETDRIARELAAATGESITVAARIAMEERLRRVRASGAEQAVRDELDAIIARGRSRRSLDDRGADEIVGYDED
GLPA

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References