Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2189545..2189816 Replicon chromosome
Accession NZ_CP119746
Organism Escherichia coli strain E15

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2189675..2189778 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2189545..2189816 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P1J19_RS10610 2186100..2186762 - 663 WP_000944256.1 exodeoxyribonuclease X -
P1J19_RS10615 2186786..2187442 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein YobB -
P1J19_RS10620 2187544..2187774 - 231 WP_000916763.1 DNA polymerase III subunit theta -
P1J19_RS10625 2187913..2188287 + 375 WP_000204699.1 CopC domain-containing protein YobA -
P1J19_RS10630 2188291..2189163 + 873 WP_000879285.1 copper homeostasis membrane protein CopD -
P1J19_RS10635 2189176..2189517 + 342 WP_000976492.1 YebY family protein -
- 2189545..2189816 - 272 - - Antitoxin
- 2189675..2189778 + 104 - - Toxin
P1J19_RS10640 2189913..2190569 + 657 WP_000812734.1 protein-serine/threonine phosphatase -
P1J19_RS10645 2190570..2190761 - 192 WP_001296140.1 YebW family protein -
P1J19_RS10650 2190866..2191102 - 237 WP_001295499.1 YebV family protein -
P1J19_RS10655 2191220..2192659 - 1440 WP_024190454.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T274397 NZ_CP119746:2189675-2189778 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT274397 NZ_CP119746:c2189816-2189545 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References