Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE(toxin)
Location 1855..2317 Replicon plasmid pE94-2
Accession NZ_CP119742
Organism Escherichia coli strain E94

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag P1J23_RS26885 Protein ID WP_276171355.1
Coordinates 1855..2136 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag P1J23_RS26890 Protein ID WP_001426295.1
Coordinates 2126..2317 (-) Length 64 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P1J23_RS26870 (892) 892..1107 - 216 WP_001180116.1 hypothetical protein -
P1J23_RS26875 (1097) 1097..1342 - 246 WP_000356545.1 hypothetical protein -
P1J23_RS26880 (1387) 1387..1641 - 255 WP_230905640.1 hypothetical protein -
P1J23_RS26885 (1855) 1855..2136 - 282 WP_276171355.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
P1J23_RS26890 (2126) 2126..2317 - 192 WP_001426295.1 hypothetical protein Antitoxin
P1J23_RS26895 (3611) 3611..4447 + 837 WP_001050931.1 RepB family plasmid replication initiator protein -
P1J23_RS26900 (4487) 4487..4738 + 252 Protein_7 hypothetical protein -
P1J23_RS26905 (4928) 4928..6117 - 1190 Protein_8 IS91 family transposase -
P1J23_RS26910 (6117) 6117..6482 - 366 WP_000091308.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - estIa 1..101030 101030
- inside IScluster/Tn - - 30..7946 7916


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-82)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 11006.78 Da        Isoelectric Point: 10.5938

>T274383 WP_276171355.1 NZ_CP119742:c2136-1855 [Escherichia coli]
MTYELAFDRRALKEWQKLGHTIREQFKKKLAERLENPRVPAARLHGHADRYKNKLRASGYRLVYQVIDEKVVLLVIAVGR
RESSEVYQIADLR

Download         Length: 282 bp

Antitoxin


Download         Length: 64 a.a.        Molecular weight: 7015.90 Da        Isoelectric Point: 3.9944

>AT274383 WP_001426295.1 NZ_CP119742:c2317-2126 [Escherichia coli]
MGTVAEGEGDAVAILNRNEPAFYCVPPKLYAYYRELAEDAELNAVADERMKNPEIVKVNLDDL

Download         Length: 192 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References