Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2175494..2175765 Replicon chromosome
Accession NZ_CP119740
Organism Escherichia coli strain E94

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2175624..2175727 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2175494..2175765 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P1J23_RS10805 2172049..2172711 - 663 WP_000944256.1 exodeoxyribonuclease X -
P1J23_RS10810 2172735..2173391 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
P1J23_RS10815 2173493..2173723 - 231 WP_000916763.1 DNA polymerase III subunit theta -
P1J23_RS10820 2173862..2174236 + 375 WP_000204699.1 CopC domain-containing protein YobA -
P1J23_RS10825 2174240..2175112 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
P1J23_RS10830 2175125..2175466 + 342 WP_000976492.1 YebY family protein -
- 2175494..2175765 - 272 - - Antitoxin
- 2175624..2175727 + 104 - - Toxin
P1J23_RS10835 2175862..2176269 + 408 Protein_2117 metallophosphoesterase -
P1J23_RS10840 2176346..2177269 + 924 WP_001118645.1 IS5 family transposase -
P1J23_RS10845 2177326..2177583 + 258 Protein_2119 serine/threonine-protein phosphatase -
P1J23_RS10850 2177584..2177775 - 192 WP_001296140.1 YebW family protein -
P1J23_RS10855 2177880..2178116 - 237 WP_001295499.1 YebV family protein -
P1J23_RS10860 2178234..2179673 - 1440 WP_000057023.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 2176346..2177269 923


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T274371 NZ_CP119740:2175624-2175727 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT274371 NZ_CP119740:c2175765-2175494 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References