Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 625228..625910 Replicon plasmid p2
Accession NZ_CP119567
Organism Pararhizobium sp. T808

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PYR65_RS24100 Protein ID WP_276121277.1
Coordinates 625228..625659 (-) Length 144 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PYR65_RS24105 Protein ID WP_276121278.1
Coordinates 625656..625910 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PYR65_RS24085 620775..623432 + 2658 WP_276121274.1 nitrate reductase -
PYR65_RS24090 623404..624894 + 1491 WP_276121275.1 siroheme synthase CysG -
PYR65_RS24095 624891..625211 + 321 WP_276121276.1 hypothetical protein -
PYR65_RS24100 625228..625659 - 432 WP_276121277.1 type II toxin-antitoxin system VapC family toxin Toxin
PYR65_RS24105 625656..625910 - 255 WP_276121278.1 plasmid stabilization protein Antitoxin
PYR65_RS24110 626069..626398 - 330 WP_276121279.1 cupin domain-containing protein -
PYR65_RS24115 626410..627165 - 756 WP_276121280.1 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD -
PYR65_RS24120 627162..628004 - 843 WP_276121281.1 5-dehydro-4-deoxy-D-glucuronate isomerase -
PYR65_RS24125 628036..628773 - 738 WP_060636901.1 ATP-binding cassette domain-containing protein -
PYR65_RS24130 628773..629792 - 1020 WP_200953565.1 ABC transporter permease -
PYR65_RS24135 629865..630815 - 951 WP_060636619.1 substrate-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - htpB 1..900497 900497


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 144 a.a.        Molecular weight: 15602.11 Da        Isoelectric Point: 4.8839

>T274204 WP_276121277.1 NZ_CP119567:c625659-625228 [Pararhizobium sp. T808]
MILLDTNVISEPWKPAPDETVVAWLDAQAVETLFISAITIAELRFGIAAMPAGKRQTILRDRLEVEVLPHFAGRILPFGV
ATSQFYSELMVRARLSGKAIGEADGYIAATAAENRLAVATRDINPFEAAGLKVINPWILQQLS

Download         Length: 432 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9224.49 Da        Isoelectric Point: 6.2275

>AT274204 WP_276121278.1 NZ_CP119567:c625910-625656 [Pararhizobium sp. T808]
MPAVIIRNLSEETHRALKVRAAHHGRSTEAEIRDIIEAAVRPAERVKLGSLLAAIGRDAELSDTDVEVLQQNRGKAPAEP
MTFE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References