Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 3589006..3589601 Replicon chromosome
Accession NZ_CP119566
Organism Pararhizobium sp. T808

Toxin (Protein)


Gene name PumA Uniprot ID A0A0Q7P9Y0
Locus tag PYR65_RS17650 Protein ID WP_060636412.1
Coordinates 3589311..3589601 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0Q7PLU6
Locus tag PYR65_RS17645 Protein ID WP_060636411.1
Coordinates 3589006..3589299 (-) Length 98 a.a.

Genomic Context

PYR65_RS17605PYR65_RS17610PYR65_RS17615PYR65_RS17620PYR65_RS17625PYR65_RS17630PYR65_RS17635PYR65_RS17640PYR65_RS17645PYR65_RS17650PYR65_RS17655PYR65_RS17660PYR65_RS17665PYR65_RS17670PYR65_RS17675
Location: 3584017..3584313 (297 bp)
Type: Others
Protein ID: WP_276118910.1
Location: 3584330..3584731 (402 bp)
Type: Others
Protein ID: WP_276118911.1
Location: 3584735..3585178 (444 bp)
Type: Others
Protein ID: WP_060636406.1
Location: 3585175..3586155 (981 bp)
Type: Others
Protein ID: WP_276118912.1
Location: 3586340..3587350 (1011 bp)
Type: Others
Protein ID: WP_276118913.1
Location: 3587354..3587719 (366 bp)
Type: Others
Protein ID: WP_276118914.1
Location: 3587751..3588521 (771 bp)
Type: Others
Protein ID: WP_276121096.1
Location: 3588490..3588873 (384 bp)
Type: Others
Protein ID: WP_276118915.1
Location: 3589006..3589299 (294 bp)
Type: Antitoxin
Protein ID: WP_060636411.1
Location: 3589311..3589601 (291 bp)
Type: Toxin
Protein ID: WP_060636412.1
Location: 3589711..3590586 (876 bp)
Type: Others
Protein ID: WP_060636413.1
Location: 3590652..3591260 (609 bp)
Type: Others
Protein ID: WP_060636414.1
Location: 3591270..3591410 (141 bp)
Type: Others
Protein ID: WP_060636415.1
Location: 3591410..3592366 (957 bp)
Type: Others
Protein ID: WP_276121097.1
Location: 3592661..3594355 (1695 bp)
Type: Others
Protein ID: WP_060636417.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
PYR65_RS176053584017..3584313+297WP_276118910.1hypothetical protein-
PYR65_RS176103584330..3584731+402WP_276118911.1VOC family protein-
PYR65_RS176153584735..3585178-444WP_060636406.1ribonuclease HI-
PYR65_RS176203585175..3586155-981WP_276118912.1homoserine kinase-
PYR65_RS176253586340..3587350-1011WP_276118913.14-hydroxy-3-methylbut-2-enyl diphosphate reductase-
PYR65_RS176303587354..3587719-366WP_276118914.1DUF1304 domain-containing protein-
PYR65_RS176353587751..3588521-771WP_276121096.1SURF1 family protein-
PYR65_RS176403588490..3588873-384WP_276118915.1DUF983 domain-containing protein-
PYR65_RS176453589006..3589299-294WP_060636411.1putative addiction module antidote proteinAntitoxin
PYR65_RS176503589311..3589601-291WP_060636412.1type II toxin-antitoxin system RelE/ParE family toxinToxin
PYR65_RS176553589711..3590586-876WP_060636413.1cytochrome c oxidase subunit 3-
PYR65_RS176603590652..3591260-609WP_060636414.1cytochrome c oxidase assembly protein-
PYR65_RS176653591270..3591410-141WP_060636415.1hypothetical protein-
PYR65_RS176703591410..3592366-957WP_276121097.1heme o synthase-
PYR65_RS176753592661..3594355-1695WP_060636417.1cytochrome c oxidase subunit I-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(4-95)

Antitoxin

Uncharacterized protein HI1420

(3-89)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10756.56 Da        Isoelectric Point: 10.2260

>T274201 WP_060636412.1 NZ_CP119566:c3589601-3589311 [Pararhizobium sp. T808]
MLVFETTDVFKDWLFSLRDVKAKARILARIRSAEFGNLGDCAPVGEGVSEMRIHYGPGYRLYFKRRGDVVYLLLAGGDKS
SQKRDIAAALKMAKSL

Download         Length: 291 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10536.95 Da        Isoelectric Point: 4.6313

>AT274201 WP_060636411.1 NZ_CP119566:c3589299-3589006 [Pararhizobium sp. T808]
MTTVSRFDASEFLDDDDLVAEYLTAAMEDDNPDVFIAALGDVAKARGMTEIARASGLGRESLYKSLRGGSKARFETLHKI
VNTLGLKMTIVADRPTP

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A0Q7P9Y0

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A0Q7PLU6

References