Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/HicB-HicA
Location 3479456..3480053 Replicon chromosome
Accession NZ_CP119566
Organism Pararhizobium sp. T808

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag PYR65_RS17015 Protein ID WP_276121089.1
Coordinates 3479456..3479644 (+) Length 63 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag PYR65_RS17020 Protein ID WP_276118824.1
Coordinates 3479649..3480053 (+) Length 135 a.a.

Genomic Context

PYR65_RS17000PYR65_RS17010PYR65_RS17015PYR65_RS17020PYR65_RS17045PYR65_RS16990PYR65_RS16995PYR65_RS17005PYR65_RS17025PYR65_RS17030PYR65_RS17035PYR65_RS17040PYR65_RS17050PYR65_RS17055
Location: 3475110..3477452 (2343 bp)
Type: Others
Protein ID: WP_276118821.1
Location: 3478818..3479309 (492 bp)
Type: Others
Protein ID: WP_276118823.1
Location: 3479456..3479644 (189 bp)
Type: Toxin
Protein ID: WP_276121089.1
Location: 3479649..3480053 (405 bp)
Type: Antitoxin
Protein ID: WP_276118824.1
Location: 3482767..3483483 (717 bp)
Type: Others
Protein ID: WP_276118827.1
Location: 3474518..3474757 (240 bp)
Type: Others
Protein ID: WP_276118819.1
Location: 3474797..3475132 (336 bp)
Type: Others
Protein ID: WP_276118820.1
Location: 3477558..3478442 (885 bp)
Type: Others
Protein ID: WP_276118822.1
Location: 3480069..3480278 (210 bp)
Type: Others
Protein ID: WP_276118825.1
Location: 3480354..3481271 (918 bp)
Type: Others
Protein ID: WP_276118826.1
Location: 3481379..3481816 (438 bp)
Type: Others
Protein ID: WP_060639884.1
Location: 3482000..3482630 (631 bp)
Type: Others
Protein ID: Protein_3352
Location: 3483485..3483715 (231 bp)
Type: Others
Protein ID: WP_276118828.1
Location: 3483810..3484655 (846 bp)
Type: Others
Protein ID: WP_276118829.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
PYR65_RS169903474518..3474757-240WP_276118819.1hypothetical protein-
PYR65_RS169953474797..3475132-336WP_276118820.1hypothetical protein-
PYR65_RS170003475110..3477452+2343WP_276118821.1glucose/quinate/shikimate family membrane-bound PQQ-dependent dehydrogenase-
PYR65_RS170053477558..3478442-885WP_276118822.1class A beta-lactamase-
PYR65_RS170103478818..3479309+492WP_276118823.1GNAT family N-acetyltransferase-
PYR65_RS170153479456..3479644+189WP_276121089.1type II toxin-antitoxin system HicA family toxinToxin
PYR65_RS170203479649..3480053+405WP_276118824.1type II toxin-antitoxin system HicB family antitoxinAntitoxin
PYR65_RS170253480069..3480278-210WP_276118825.1type II toxin-antitoxin system HicB family antitoxin-
PYR65_RS170303480354..3481271-918WP_276118826.1cytochrome c-
PYR65_RS170353481379..3481816-438WP_060639884.1cytochrome c-
PYR65_RS170403482000..3482630-631Protein_3352LysE family translocator-
PYR65_RS170453482767..3483483+717WP_276118827.1YafY family protein-
PYR65_RS170503483485..3483715-231WP_276118828.1hypothetical protein-
PYR65_RS170553483810..3484655-846WP_276118829.1metallophosphoesterase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(4-59)

Antitoxin

HicB-like antitoxin of toxin-antitoxin system

(4-124)


Sequences

Toxin        


Download         Length: 63 a.a.        Molecular weight: 7027.16 Da        Isoelectric Point: 11.1468

>T274199 WP_276121089.1 NZ_CP119566:3479456-3479644 [Pararhizobium sp. T808]
ILSSDVISNLRKDGWYEVARKGSHVQFKHPGKPGRVTVPHPRRDIPIGTLKSIEKQADLKLR

Download         Length: 189 bp

Antitoxin


Download         Length: 135 a.a.        Molecular weight: 14495.31 Da        Isoelectric Point: 4.4454

>AT274199 WP_276118824.1 NZ_CP119566:3479649-3480053 [Pararhizobium sp. T808]
MRNYIGLIHKDPGSDYGVSFPDFPGVISAGTDLDDARQMASEALAFHLEGLVEDGSNIPEPSSLENIMADADNRKGVAIL
VGVRMETKKAVRVNVTLPEDVLRQIDRFAESKGLTRSGFIALAALHEIDRDDAA

Download         Length: 405 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References