Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) BrnTA/BrnT-BrnA
Location 1275355..1275913 Replicon chromosome
Accession NZ_CP119566
Organism Pararhizobium sp. T808

Toxin (Protein)


Gene name brnT Uniprot ID -
Locus tag PYR65_RS06045 Protein ID WP_276120304.1
Coordinates 1275355..1275609 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name brnA Uniprot ID -
Locus tag PYR65_RS06050 Protein ID WP_276120305.1
Coordinates 1275596..1275913 (+) Length 106 a.a.

Genomic Context

PYR65_RS06005PYR65_RS06010PYR65_RS06025PYR65_RS06035PYR65_RS06040PYR65_RS06045PYR65_RS06050PYR65_RS06055PYR65_RS06060PYR65_RS06065PYR65_RS06070PYR65_RS06080PYR65_RS06085PYR65_RS06020PYR65_RS06030PYR65_RS06075
Location: 1271277..1271549 (273 bp)
Type: Others
Protein ID: WP_060639397.1
Location: 1271580..1271957 (378 bp)
Type: Others
Protein ID: WP_276120299.1
Location: 1273176..1273397 (222 bp)
Type: Others
Protein ID: WP_276120301.1
Location: 1273887..1274498 (612 bp)
Type: Others
Protein ID: WP_276120302.1
Location: 1274476..1275300 (825 bp)
Type: Others
Protein ID: WP_276120303.1
Location: 1275355..1275609 (255 bp)
Type: Toxin
Protein ID: WP_276120304.1
Location: 1275596..1275913 (318 bp)
Type: Antitoxin
Protein ID: WP_276120305.1
Location: 1276031..1276870 (840 bp)
Type: Others
Protein ID: WP_276120306.1
Location: 1276888..1277367 (480 bp)
Type: Others
Protein ID: WP_276120307.1
Location: 1277455..1278201 (747 bp)
Type: Others
Protein ID: WP_037099910.1
Location: 1278294..1278650 (357 bp)
Type: Others
Protein ID: WP_276120308.1
Location: 1279875..1280387 (513 bp)
Type: Others
Protein ID: WP_276120981.1
Location: 1280442..1280690 (249 bp)
Type: Others
Protein ID: WP_276120310.1
Location: 1272199..1273071 (873 bp)
Type: Others
Protein ID: WP_276120300.1
Location: 1273392..1273604 (213 bp)
Type: Others
Protein ID: WP_060639582.1
Location: 1278700..1279701 (1002 bp)
Type: Others
Protein ID: WP_276120309.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
PYR65_RS060051271277..1271549+273WP_060639397.1DUF4164 domain-containing protein-
PYR65_RS060101271580..1271957+378WP_276120299.1cell division protein ZapA-
PYR65_RS060201272199..1273071-873WP_276120300.1LysR family transcriptional regulator-
PYR65_RS060251273176..1273397+222WP_276120301.1hypothetical protein-
PYR65_RS060301273392..1273604-213WP_060639582.1LuxR C-terminal-related transcriptional regulator-
PYR65_RS060351273887..1274498+612WP_276120302.15-formyltetrahydrofolate cyclo-ligase-
PYR65_RS060401274476..1275300+825WP_276120303.1TIGR00282 family metallophosphoesterase-
PYR65_RS060451275355..1275609+255WP_276120304.1BrnT family toxinToxin
PYR65_RS060501275596..1275913+318WP_276120305.1BrnA antitoxin family proteinAntitoxin
PYR65_RS060551276031..1276870+840WP_276120306.1MBL fold metallo-hydrolase-
PYR65_RS060601276888..1277367+480WP_276120307.1hypothetical protein-
PYR65_RS060651277455..1278201+747WP_037099910.1YebC/PmpR family DNA-binding transcriptional regulator-
PYR65_RS060701278294..1278650+357WP_276120308.1cupin domain-containing protein-
PYR65_RS060751278700..1279701-1002WP_276120309.1LLM class flavin-dependent oxidoreductase-
PYR65_RS060801279875..1280387+513WP_276120981.1crossover junction endodeoxyribonuclease RuvC-
PYR65_RS060851280442..1280690+249WP_276120310.1AbrB/MazE/SpoVT family DNA-binding domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-77)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(31-103)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9682.38 Da        Isoelectric Point: 10.0519

>T274194 WP_276120304.1 NZ_CP119566:1275355-1275609 [Pararhizobium sp. T808]
MKIVYDENKRRLNLAKHGFDFVTLDMGFFQSALIVETKLNRMKAIGLFDDGKISVVFFRLGSEGISIISMRAASRMERKL
YDQC

Download         Length: 255 bp

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11958.54 Da        Isoelectric Point: 8.5600

>AT274194 WP_276120305.1 NZ_CP119566:1275596-1275913 [Pararhizobium sp. T808]
MTSAKSFKYDIPPLTDEEEARIQAGIAADPDNPEWTEEDFKRARPFAEVFPEFAESIRRSRGRPAVEARKQQVSLRLDPD
VIAKFKATGKGWQARVNEILKQAKI

Download         Length: 318 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References