Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 1536156..1536813 Replicon chromosome
Accession NZ_CP119546
Organism Providencia stuartii strain CAVP490

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag P2E05_RS06590 Protein ID WP_163860914.1
Coordinates 1536403..1536813 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag P2E05_RS06585 Protein ID WP_154624313.1
Coordinates 1536156..1536422 (+) Length 89 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P2E05_RS06570 (P2E05_06570) 1531308..1534184 + 2877 WP_163860913.1 aminomethyl-transferring glycine dehydrogenase -
P2E05_RS06575 (P2E05_06575) 1534281..1534901 - 621 WP_154624315.1 HD domain-containing protein -
P2E05_RS06580 (P2E05_06580) 1534913..1535902 - 990 WP_196713358.1 tRNA-modifying protein YgfZ -
P2E05_RS06585 (P2E05_06585) 1536156..1536422 + 267 WP_154624313.1 FAD assembly factor SdhE Antitoxin
P2E05_RS06590 (P2E05_06590) 1536403..1536813 + 411 WP_163860914.1 protein YgfX Toxin
P2E05_RS06595 (P2E05_06595) 1536858..1537376 - 519 WP_154624312.1 flavodoxin FldB -
P2E05_RS06600 (P2E05_06600) 1537461..1538384 + 924 WP_154624329.1 site-specific tyrosine recombinase XerD -
P2E05_RS06605 (P2E05_06605) 1538404..1539105 + 702 WP_154624311.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
P2E05_RS06610 (P2E05_06610) 1539115..1540848 + 1734 WP_276123059.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(3-133)

Antitoxin

(7-79)


Sequences


Toxin        


Download         Length: 137 a.a.        Molecular weight: 15375.24 Da        Isoelectric Point: 10.8779

>T274185 WP_163860914.1 NZ_CP119546:1536403-1536813 [Providencia stuartii]
VVLWKSNLSISWKTQLFSTCAHGLVGFILLVAPWAPGNSMVWLPLLAIVIASWAKSQKSISKIKGTAVLVNGNKVQWKKN
EWNIIKQPWCSRVGILLTLSALQGKQQKIRLWIAKDALSEESWRNLNQLLLQYPDI

Download         Length: 411 bp


Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10578.07 Da        Isoelectric Point: 4.7132

>AT274185 WP_154624313.1 NZ_CP119546:1536156-1536422 [Providencia stuartii]
MDIENKARIHWACRRGMRELDISIMPFFEYEYDSLSDKDKQTFVRLLECADPDLFNWLMNHGRPDDEELFGMVKLIQERN
KNRGPVEI

Download         Length: 267 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References