Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 1535999..1536656 Replicon chromosome
Accession NZ_CP119540
Organism Providencia stuartii strain CAVP496

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag P2E04_RS06585 Protein ID WP_163860914.1
Coordinates 1536246..1536656 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag P2E04_RS06580 Protein ID WP_154624313.1
Coordinates 1535999..1536265 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P2E04_RS06565 (P2E04_06565) 1531151..1534027 + 2877 WP_163860913.1 aminomethyl-transferring glycine dehydrogenase -
P2E04_RS06570 (P2E04_06570) 1534124..1534744 - 621 WP_154624315.1 HD domain-containing protein -
P2E04_RS06575 (P2E04_06575) 1534756..1535745 - 990 WP_196713358.1 tRNA-modifying protein YgfZ -
P2E04_RS06580 (P2E04_06580) 1535999..1536265 + 267 WP_154624313.1 FAD assembly factor SdhE Antitoxin
P2E04_RS06585 (P2E04_06585) 1536246..1536656 + 411 WP_163860914.1 protein YgfX Toxin
P2E04_RS06590 (P2E04_06590) 1536701..1537219 - 519 WP_154624312.1 flavodoxin FldB -
P2E04_RS06595 (P2E04_06595) 1537304..1538227 + 924 WP_154624329.1 site-specific tyrosine recombinase XerD -
P2E04_RS06600 (P2E04_06600) 1538247..1538948 + 702 WP_154624311.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
P2E04_RS06605 (P2E04_06605) 1538958..1540691 + 1734 WP_276123059.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-133)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15375.24 Da        Isoelectric Point: 10.8779

>T274181 WP_163860914.1 NZ_CP119540:1536246-1536656 [Providencia stuartii]
VVLWKSNLSISWKTQLFSTCAHGLVGFILLVAPWAPGNSMVWLPLLAIVIASWAKSQKSISKIKGTAVLVNGNKVQWKKN
EWNIIKQPWCSRVGILLTLSALQGKQQKIRLWIAKDALSEESWRNLNQLLLQYPDI

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10578.07 Da        Isoelectric Point: 4.7132

>AT274181 WP_154624313.1 NZ_CP119540:1535999-1536265 [Providencia stuartii]
MDIENKARIHWACRRGMRELDISIMPFFEYEYDSLSDKDKQTFVRLLECADPDLFNWLMNHGRPDDEELFGMVKLIQERN
KNRGPVEI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References