Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 4662979..4663532 Replicon chromosome
Accession NZ_CP119531
Organism Raoultella electrica strain Rd210413

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag P2G42_RS22300 Protein ID WP_285237531.1
Coordinates 4662979..4663293 (-) Length 105 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag P2G42_RS22305 Protein ID WP_100683473.1
Coordinates 4663296..4663532 (-) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P2G42_RS22275 (P2G42_22280) 4658501..4659199 - 699 WP_285237526.1 hypothetical protein -
P2G42_RS22280 (P2G42_22285) 4659264..4659755 - 492 WP_285237527.1 GNAT family N-acetyltransferase -
P2G42_RS22285 (P2G42_22290) 4659752..4660045 - 294 WP_285237528.1 DUF1778 domain-containing protein -
P2G42_RS22290 (P2G42_22295) 4660519..4661430 - 912 WP_285237529.1 LysR family transcriptional regulator -
P2G42_RS22295 (P2G42_22300) 4661531..4662529 + 999 WP_285237530.1 aldo/keto reductase -
P2G42_RS22300 (P2G42_22305) 4662979..4663293 - 315 WP_285237531.1 CcdB family protein Toxin
P2G42_RS22305 (P2G42_22310) 4663296..4663532 - 237 WP_100683473.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
P2G42_RS22310 (P2G42_22315) 4663712..4663877 + 166 Protein_4354 transposase -
P2G42_RS22315 (P2G42_22320) 4664095..4665243 - 1149 WP_285237532.1 MFS transporter -
P2G42_RS22320 (P2G42_22325) 4665294..4666196 - 903 WP_160704445.1 DMT family transporter -
P2G42_RS22325 (P2G42_22330) 4666467..4667501 + 1035 WP_227699466.1 iron-containing redox enzyme family protein -
P2G42_RS22330 (P2G42_22335) 4667502..4668080 - 579 WP_141963425.1 TetR/AcrR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-103)

Antitoxin

Post-segregation antitoxin CcdA

(9-78)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11512.36 Da        Isoelectric Point: 6.4489

>T274174 WP_285237531.1 NZ_CP119531:c4663293-4662979 [Raoultella electrica]
MQFTVYANTGKSTVYPLLLDVTNDIIGQLNRRIVIPLLPVDRYPAGHRPDRLVPFVSLTDGREYAVMTHELASIPVQALG
AVFCDAAQYRPQVKAAIDFLIDGI

Download         Length: 315 bp

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8929.94 Da        Isoelectric Point: 6.4798

>AT274174 WP_100683473.1 NZ_CP119531:c4663532-4663296 [Raoultella electrica]
MAAKQRSTQSVTMTVERALLARAREAGINLSATLTAALDAELRHHEAKKWQEENREAIEALNRFHDEHGCFSDEYRTF

Download         Length: 237 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References