Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 4659264..4660045 Replicon chromosome
Accession NZ_CP119531
Organism Raoultella electrica strain Rd210413

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag P2G42_RS22280 Protein ID WP_285237527.1
Coordinates 4659264..4659755 (-) Length 164 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag P2G42_RS22285 Protein ID WP_285237528.1
Coordinates 4659752..4660045 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P2G42_RS22265 (P2G42_22270) 4654800..4656710 + 1911 WP_285237524.1 hypothetical protein -
P2G42_RS22270 (P2G42_22275) 4656707..4658407 + 1701 WP_285237525.1 hypothetical protein -
P2G42_RS22275 (P2G42_22280) 4658501..4659199 - 699 WP_285237526.1 hypothetical protein -
P2G42_RS22280 (P2G42_22285) 4659264..4659755 - 492 WP_285237527.1 GNAT family N-acetyltransferase Toxin
P2G42_RS22285 (P2G42_22290) 4659752..4660045 - 294 WP_285237528.1 DUF1778 domain-containing protein Antitoxin
P2G42_RS22290 (P2G42_22295) 4660519..4661430 - 912 WP_285237529.1 LysR family transcriptional regulator -
P2G42_RS22295 (P2G42_22300) 4661531..4662529 + 999 WP_285237530.1 aldo/keto reductase -
P2G42_RS22300 (P2G42_22305) 4662979..4663293 - 315 WP_285237531.1 CcdB family protein -
P2G42_RS22305 (P2G42_22310) 4663296..4663532 - 237 WP_100683473.1 type II toxin-antitoxin system CcdA family antitoxin -
P2G42_RS22310 (P2G42_22315) 4663712..4663877 + 166 Protein_4354 transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(83-144)

Antitoxin

Vibrio phage ICP1, Orf50

(2-95)


Sequences

Toxin        


Download         Length: 164 a.a.        Molecular weight: 17757.64 Da        Isoelectric Point: 6.8438

>T274173 WP_285237527.1 NZ_CP119531:c4659755-4659264 [Raoultella electrica]
MISAPEPLHAGHILASFCCGVDSMDNWLKQRSMKNQATGASRTFVCCDSDLKVMAYYSLASSAVTMNTAPGRFRRNMPDP
IPVVVLGRLAVDQSLHGQGVGRALVRDAGLRVIQVAETIGIRGMLVHALSDDAREFYQRVGFEPSPMDPMMLMVTLGDLM
ESI

Download         Length: 492 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10832.50 Da        Isoelectric Point: 10.1982

>AT274173 WP_285237528.1 NZ_CP119531:c4660045-4659752 [Raoultella electrica]
MPAANSMAMKRETLNLRIKPAERDLIDRAAKAKGKNRTDFVLEAARAAAEEALIEQRIIMADPEAYQAFLTRLDQAPAPN
AALRKTMQTPAPWEQKN

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References