Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 4659264..4660045 Replicon chromosome
Accession NZ_CP119531
Organism Raoultella electrica strain Rd210413

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag P2G42_RS22280 Protein ID WP_285237527.1
Coordinates 4659264..4659755 (-) Length 164 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag P2G42_RS22285 Protein ID WP_285237528.1
Coordinates 4659752..4660045 (-) Length 98 a.a.

Genomic Context

P2G42_RS22265P2G42_RS22270P2G42_RS22295P2G42_RS22310P2G42_RS22275P2G42_RS22280P2G42_RS22285P2G42_RS22290P2G42_RS22300P2G42_RS22305
Location: 4654800..4656710 (1911 bp)
Type: Others
Protein ID: WP_285237524.1
Location: 4656707..4658407 (1701 bp)
Type: Others
Protein ID: WP_285237525.1
Location: 4661531..4662529 (999 bp)
Type: Others
Protein ID: WP_285237530.1
Location: 4663712..4663877 (166 bp)
Type: Others
Protein ID: Protein_4354
Location: 4658501..4659199 (699 bp)
Type: Others
Protein ID: WP_285237526.1
Location: 4659264..4659755 (492 bp)
Type: Toxin
Protein ID: WP_285237527.1
Location: 4659752..4660045 (294 bp)
Type: Antitoxin
Protein ID: WP_285237528.1
Location: 4660519..4661430 (912 bp)
Type: Others
Protein ID: WP_285237529.1
Location: 4662979..4663293 (315 bp)
Type: Others
Protein ID: WP_285237531.1
Location: 4663296..4663532 (237 bp)
Type: Others
Protein ID: WP_100683473.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
P2G42_RS22265 (P2G42_22270)4654800..4656710+1911WP_285237524.1hypothetical protein-
P2G42_RS22270 (P2G42_22275)4656707..4658407+1701WP_285237525.1hypothetical protein-
P2G42_RS22275 (P2G42_22280)4658501..4659199-699WP_285237526.1hypothetical protein-
P2G42_RS22280 (P2G42_22285)4659264..4659755-492WP_285237527.1GNAT family N-acetyltransferaseToxin
P2G42_RS22285 (P2G42_22290)4659752..4660045-294WP_285237528.1DUF1778 domain-containing proteinAntitoxin
P2G42_RS22290 (P2G42_22295)4660519..4661430-912WP_285237529.1LysR family transcriptional regulator-
P2G42_RS22295 (P2G42_22300)4661531..4662529+999WP_285237530.1aldo/keto reductase-
P2G42_RS22300 (P2G42_22305)4662979..4663293-315WP_285237531.1CcdB family protein-
P2G42_RS22305 (P2G42_22310)4663296..4663532-237WP_100683473.1type II toxin-antitoxin system CcdA family antitoxin-
P2G42_RS22310 (P2G42_22315)4663712..4663877+166Protein_4354transposase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(83-144)

Antitoxin

Vibrio phage ICP1, Orf50

(2-95)


Sequences

Toxin        


Download         Length: 164 a.a.        Molecular weight: 17757.64 Da        Isoelectric Point: 6.8438

>T274173 WP_285237527.1 NZ_CP119531:c4659755-4659264 [Raoultella electrica]
MISAPEPLHAGHILASFCCGVDSMDNWLKQRSMKNQATGASRTFVCCDSDLKVMAYYSLASSAVTMNTAPGRFRRNMPDP
IPVVVLGRLAVDQSLHGQGVGRALVRDAGLRVIQVAETIGIRGMLVHALSDDAREFYQRVGFEPSPMDPMMLMVTLGDLM
ESI

Download         Length: 492 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10832.50 Da        Isoelectric Point: 10.1982

>AT274173 WP_285237528.1 NZ_CP119531:c4660045-4659752 [Raoultella electrica]
MPAANSMAMKRETLNLRIKPAERDLIDRAAKAKGKNRTDFVLEAARAAAEEALIEQRIIMADPEAYQAFLTRLDQAPAPN
AALRKTMQTPAPWEQKN

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References