Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 2733167..2733918 Replicon chromosome
Accession NZ_CP119531
Organism Raoultella electrica strain Rd210413

Toxin (Protein)


Gene name ataT Uniprot ID -
Locus tag P2G42_RS12860 Protein ID WP_141964594.1
Coordinates 2733167..2733649 (-) Length 161 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag P2G42_RS12865 Protein ID WP_100683705.1
Coordinates 2733640..2733918 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P2G42_RS12830 (P2G42_12830) 2728905..2729469 - 565 Protein_2499 SOS response-associated peptidase family protein -
P2G42_RS12835 (P2G42_12835) 2729730..2730233 - 504 WP_131050351.1 Imm70 family immunity protein -
P2G42_RS12840 (P2G42_12840) 2730539..2731030 - 492 Protein_2501 DUF637 domain-containing protein -
P2G42_RS12845 (P2G42_12845) 2731076..2731522 + 447 Protein_2502 helix-turn-helix domain-containing protein -
P2G42_RS12850 (P2G42_12850) 2731629..2732420 + 792 WP_131050353.1 tetratricopeptide repeat protein -
P2G42_RS12855 (P2G42_12855) 2732580..2733116 - 537 WP_100683703.1 dihydrofolate reductase family protein -
P2G42_RS12860 (P2G42_12860) 2733167..2733649 - 483 WP_141964594.1 GNAT family N-acetyltransferase Toxin
P2G42_RS12865 (P2G42_12865) 2733640..2733918 - 279 WP_100683705.1 DUF1778 domain-containing protein Antitoxin
P2G42_RS12870 (P2G42_12870) 2733998..2734600 - 603 WP_160704955.1 DJ-1/PfpI family protein -
P2G42_RS12875 (P2G42_12875) 2735161..2736186 + 1026 WP_100683707.1 amino acid ABC transporter substrate-binding protein -
P2G42_RS12880 (P2G42_12880) 2736257..2737435 + 1179 WP_131050357.1 amino acid ABC transporter permease -
P2G42_RS12885 (P2G42_12885) 2737451..2738551 + 1101 WP_131050358.1 amino acid ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element blaPLA-4A - 2703660..3034025 330365


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(75-146)

Antitoxin

Vibrio phage ICP1, Orf50

(10-86)


Sequences

Toxin        


Download         Length: 161 a.a.        Molecular weight: 17681.43 Da        Isoelectric Point: 9.1567

>T274166 WP_141964594.1 NZ_CP119531:c2733649-2733167 [Raoultella electrica]
MGMRPPESLTPEHDIAEFCCQDPGLNEWLKKKALKNHSTGISRVYVVCAGNTNRVIAYYCLSSGSVHRNTVPGTYRRNAP
ESVPVIVQGRLAVDVSWAGKGLGAALLKDAIYRTQNIAVQVGVRALLVHALNDEVRDFYTRFGFEPSIVNVLTLLFPIRL

Download         Length: 483 bp

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10740.28 Da        Isoelectric Point: 4.5533

>AT274166 WP_100683705.1 NZ_CP119531:c2733918-2733640 [Raoultella electrica]
MKPDIREAPINIRAKTSQRDLIDMAANLVSKSRTDFMLEAACREAQDILLDQRLFLLDDKQFESFIEELDAPMTAERQAR
IDNLMNRKSPWE

Download         Length: 279 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References