Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) hipBA/HipA-HipB
Location 2695762..2697365 Replicon chromosome
Accession NZ_CP119531
Organism Raoultella electrica strain Rd210413

Toxin (Protein)


Gene name hipA Uniprot ID -
Locus tag P2G42_RS12700 Protein ID WP_285236926.1
Coordinates 2696034..2697365 (+) Length 444 a.a.

Antitoxin (Protein)


Gene name hipB Uniprot ID -
Locus tag P2G42_RS12695 Protein ID WP_131049088.1
Coordinates 2695762..2696034 (+) Length 91 a.a.

Genomic Context


P2G42_RS12680P2G42_RS12685P2G42_RS12690P2G42_RS12695P2G42_RS12700P2G42_RS12710P2G42_RS12715P2G42_RS12670P2G42_RS12675P2G42_RS12705
Location: 2693219..2694460 (1242 bp)
Type: Others
Protein ID: WP_285236924.1
Location: 2694580..2694996 (417 bp)
Type: Others
Protein ID: WP_160703369.1
Location: 2695002..2695556 (555 bp)
Type: Others
Protein ID: WP_285236925.1
Location: 2695762..2696034 (273 bp)
Type: Antitoxin
Protein ID: WP_131049088.1
Location: 2696034..2697365 (1332 bp)
Type: Toxin
Protein ID: WP_285236926.1
Location: 2699409..2700467 (1059 bp)
Type: Others
Protein ID: WP_206057711.1
Location: 2700558..2701472 (915 bp)
Type: Others
Protein ID: WP_100684215.1
Location: 2691250..2691978 (729 bp)
Type: Others
Protein ID: WP_285236923.1
Location: 2691975..2692667 (693 bp)
Type: Others
Protein ID: WP_141964609.1
Location: 2697298..2698704 (1407 bp)
Type: Others
Protein ID: WP_285238309.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
P2G42_RS12670 (P2G42_12670)2691250..2691978-729WP_285236923.1ABC transporter ATP-binding protein-
P2G42_RS12675 (P2G42_12675)2691975..2692667-693WP_141964609.1TenA family protein-
P2G42_RS12680 (P2G42_12680)2693219..2694460+1242WP_285236924.1sensor domain-containing diguanylate cyclase-
P2G42_RS12685 (P2G42_12685)2694580..2694996+417WP_160703369.1hypothetical protein-
P2G42_RS12690 (P2G42_12690)2695002..2695556+555WP_285236925.1sigma-70 family RNA polymerase sigma factor-
P2G42_RS12695 (P2G42_12695)2695762..2696034+273WP_131049088.1type II toxin-antitoxin system antitoxin HipBAntitoxin
P2G42_RS12700 (P2G42_12700)2696034..2697365+1332WP_285236926.1type II toxin-antitoxin system HipA family toxinToxin
P2G42_RS12705 (P2G42_12705)2697298..2698704-1407WP_285238309.1glycoside hydrolase family 10 protein-
P2G42_RS12710 (P2G42_12710)2699409..2700467+1059WP_206057711.1branched-chain amino acid ABC transporter substrate-binding protein-
P2G42_RS12715 (P2G42_12715)2700558..2701472+915WP_100684215.1branched-chain amino acid ABC transporter permease LivH-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(149-402)

Antitoxin

(14-68)


Sequences


Toxin        


Download         Length: 444 a.a.        Molecular weight: 49403.78 Da        Isoelectric Point: 7.1616

>T274165 WP_285236926.1 NZ_CP119531:2696034-2697365 [Raoultella electrica]
MATLVTWMNNERVGELIKQANGAHLFRYEEAWMRNPRARPLSLSLPLQYGNITDEAVFNYFDNLLPDSPRVRDRIVKRYQ
ARSKQPFDLLAEIGRDSVGAVTLLPPGENAPRGALSWEPLDNHALDMLLTAYRSDIPLGMVNEHDDFRISVAGAQEKTAL
LKIGEQWCIPTGTTPTTHIIKLPIGEIKQPDAVLDLSESVDNEYLCLALARALGFAVPQASIIQTASTRALAVERFDRRW
AQEKTVLLRLPQEDLCQAFGIPSSVKYESDGGPGIRAIMAFLVGSSEALEDRYNFMKFMVFQWLIGATDGHAKNFSIYLQ
PGGSYRLTPFYDIISAFPLLGGKGLHLSDLKLSMSLKASKGRKTEIQTLYPRHFLATAKEVGFARPQMLEILRYFVDNVP
RAVDAVKGTLPPDFSQPVYEAITDRLLWVHSRLQNAMAASPAG

Download         Length: 1332 bp


Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10264.61 Da        Isoelectric Point: 6.9745

>AT274165 WP_131049088.1 NZ_CP119531:2695762-2696034 [Raoultella electrica]
MSPSPTIYSPVQLANYLKLVRQKNQWTQSDLAQRMGIKQATVSNFENHPEKTTLTTVFKILQSLELSMVICEKNAPDSGN
NRDNPQDLDW

Download         Length: 273 bp


Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
No matching records found

References