Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 1333195..1333814 Replicon chromosome
Accession NZ_CP119531
Organism Raoultella electrica strain Rd210413

Toxin (Protein)


Gene name Hha Uniprot ID A0A514EV16
Locus tag P2G42_RS06255 Protein ID WP_004858783.1
Coordinates 1333195..1333413 (-) Length 73 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID A0A514EV88
Locus tag P2G42_RS06260 Protein ID WP_004858785.1
Coordinates 1333440..1333814 (-) Length 125 a.a.

Genomic Context

P2G42_RS06220P2G42_RS06225P2G42_RS06235P2G42_RS06245P2G42_RS06230P2G42_RS06240P2G42_RS06250P2G42_RS06255P2G42_RS06260P2G42_RS06265P2G42_RS06270
Location: 1329266..1329526 (261 bp)
Type: Others
Protein ID: WP_004858777.1
Location: 1329529..1329669 (141 bp)
Type: Others
Protein ID: WP_003859006.1
Location: 1330487..1331932 (1446 bp)
Type: Others
Protein ID: WP_285237917.1
Location: 1332371..1332505 (135 bp)
Type: Others
Protein ID: WP_224742582.1
Location: 1329666..1330376 (711 bp)
Type: Others
Protein ID: WP_100683167.1
Location: 1331907..1332377 (471 bp)
Type: Others
Protein ID: WP_100683169.1
Location: 1332477..1333043 (567 bp)
Type: Others
Protein ID: WP_100683170.1
Location: 1333195..1333413 (219 bp)
Type: Toxin
Protein ID: WP_004858783.1
Location: 1333440..1333814 (375 bp)
Type: Antitoxin
Protein ID: WP_004858785.1
Location: 1334340..1337486 (3147 bp)
Type: Others
Protein ID: WP_131047523.1
Location: 1337509..1338702 (1194 bp)
Type: Others
Protein ID: WP_100683172.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
P2G42_RS06220 (P2G42_06220)1329266..1329526+261WP_004858777.1type B 50S ribosomal protein L31-
P2G42_RS06225 (P2G42_06225)1329529..1329669+141WP_003859006.1type B 50S ribosomal protein L36-
P2G42_RS06230 (P2G42_06230)1329666..1330376-711WP_100683167.1GNAT family protein-
P2G42_RS06235 (P2G42_06235)1330487..1331932+1446WP_285237917.1PLP-dependent aminotransferase family protein-
P2G42_RS06240 (P2G42_06240)1331907..1332377-471WP_100683169.1YlaC family protein-
P2G42_RS06245 (P2G42_06245)1332371..1332505+135WP_224742582.1hypothetical protein-
P2G42_RS06250 (P2G42_06250)1332477..1333043-567WP_100683170.1maltose O-acetyltransferase-
P2G42_RS06255 (P2G42_06255)1333195..1333413-219WP_004858783.1HHA domain-containing proteinToxin
P2G42_RS06260 (P2G42_06260)1333440..1333814-375WP_004858785.1Hha toxicity modulator TomBAntitoxin
P2G42_RS06265 (P2G42_06265)1334340..1337486-3147WP_131047523.1multidrug efflux RND transporter permease subunit AcrB-
P2G42_RS06270 (P2G42_06270)1337509..1338702-1194WP_100683172.1multidrug efflux RND transporter periplasmic adaptor subunit AcrA-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(13-69)

Antitoxin

Biofilm formation regulator YbaJ

(1-116)


Sequences

Toxin        


Download         Length: 73 a.a.        Molecular weight: 8570.90 Da        Isoelectric Point: 7.9907

>T274164 WP_004858783.1 NZ_CP119531:c1333413-1333195 [Raoultella electrica]
MSGEPLTKTDYLMRLRRCQTIDTLERVIEKNKYELSDNELAVFYSAADHRLAELTMNKLYDKIPTSVWKFIR

Download         Length: 219 bp

Antitoxin


Download         Length: 125 a.a.        Molecular weight: 14411.19 Da        Isoelectric Point: 4.8989

>AT274164 WP_004858785.1 NZ_CP119531:c1333814-1333440 [Raoultella electrica]
MDEYSPKRHDIAQLRFLCETLYHDCLANLEESNHGWVNDPTSAINLQLNELIEHIATFALNYKIKYAEDNKLIAQLDEYL
DDTFMLFSSYGINTADLQKWRKSGNRLFRCFVNASRENPASLSC

Download         Length: 375 bp


Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
AlphaFold DBA0A514EV16

Antitoxin

Loading, please wait
Source
ID
Structure
AlphaFold DBA0A514EV88

References