Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) shpAB/BrnT-BrnA
Location 782436..783012 Replicon chromosome
Accession NZ_CP119531
Organism Raoultella electrica strain Rd210413

Toxin (Protein)


Gene name shpA Uniprot ID -
Locus tag P2G42_RS03665 Protein ID WP_131049471.1
Coordinates 782436..782723 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name shpB Uniprot ID -
Locus tag P2G42_RS03670 Protein ID WP_141965380.1
Coordinates 782710..783012 (+) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P2G42_RS03650 (P2G42_03650) 779886..780668 - 783 WP_141965383.1 NAD(P)H-dependent oxidoreductase -
P2G42_RS03655 (P2G42_03655) 780756..781664 + 909 WP_141965382.1 LysR family transcriptional regulator -
P2G42_RS03660 (P2G42_03660) 781658..782101 + 444 WP_141965381.1 FosA family fosfomycin resistance glutathione transferase -
P2G42_RS03665 (P2G42_03665) 782436..782723 + 288 WP_131049471.1 BrnT family toxin Toxin
P2G42_RS03670 (P2G42_03670) 782710..783012 + 303 WP_141965380.1 BrnA antitoxin family protein Antitoxin
P2G42_RS03675 (P2G42_03675) 783153..784565 - 1413 WP_285237810.1 PLP-dependent aminotransferase family protein -
P2G42_RS03680 (P2G42_03680) 784743..784907 + 165 WP_100684675.1 DUF1127 domain-containing protein -
P2G42_RS03685 (P2G42_03685) 785506..785970 + 465 WP_141965379.1 MarR family transcriptional regulator -
P2G42_RS03690 (P2G42_03690) 785974..787041 + 1068 WP_141965378.1 HlyD family secretion protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(7-88)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(37-93)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11135.61 Da        Isoelectric Point: 8.5787

>T274163 WP_131049471.1 NZ_CP119531:782436-782723 [Raoultella electrica]
MPMEFEWDANKAASNLRKHGIRFEEAVLVFDDPQHLSRQDRYQNGEYRWQTLGLVHGIIVILVAHSVRFESGTEVIRIIS
ARKADKKERSRYEHG

Download         Length: 288 bp

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 11564.11 Da        Isoelectric Point: 9.7962

>AT274163 WP_141965380.1 NZ_CP119531:782710-783012 [Raoultella electrica]
MNMVKHKRDNPAALTAQREDELKALAKKSDDDIDYSDIPSSDDEQWSEAVRGKFYRPLKTQASVRIDADVMAWLKRPGKG
YQTRLNAILREAMLREQNKK

Download         Length: 303 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References