Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-MazE
Location 1424507..1425138 Replicon chromosome
Accession NZ_CP119409
Organism Rhizobium gei strain ZFJT.2T

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PY308_RS06675 Protein ID WP_275789440.1
Coordinates 1424734..1425138 (+) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PY308_RS06670 Protein ID WP_275791042.1
Coordinates 1424507..1424737 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PY308_RS06660 1419807..1420700 + 894 WP_275789437.1 DsbA family protein -
PY308_RS06665 1420977..1424441 + 3465 WP_275789438.1 chromosome segregation SMC family protein -
PY308_RS06670 1424507..1424737 + 231 WP_275791042.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
PY308_RS06675 1424734..1425138 + 405 WP_275789440.1 PIN domain-containing protein Toxin
PY308_RS06680 1425298..1427964 + 2667 WP_275789443.1 pyruvate, phosphate dikinase -
PY308_RS06685 1428077..1428499 + 423 WP_275789445.1 YciI family protein -
PY308_RS06690 1428553..1429815 + 1263 WP_275789447.1 RNA polymerase sigma factor -
PY308_RS06695 1429824..1430078 - 255 WP_275789449.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-115)

Antitoxin

SpoVT-AbrB domain

(5-47)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14786.00 Da        Isoelectric Point: 6.4821

>T274127 WP_275789440.1 NZ_CP119409:1424734-1425138 [Rhizobium gei]
MRAFFDTNILVYAFSTDPKREQANATIAEGGVISAQVLNELTHVFRRKQKKEWPAIEAALKLMTSRLAEIVPLTAELHAA
ALPIARDHGLTIYDALIVAAAMEAGCDTLFSEDMQHGRTFDRLTIRNPFLGTSA

Download         Length: 405 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8980.27 Da        Isoelectric Point: 4.7503

>AT274127 WP_275791042.1 NZ_CP119409:1424507-1424737 [Rhizobium gei]
MQVSKWGNSLAVRLPKKLVEDMALSAGDELKVVEVEDRTIVVEKVDRKAEFLREIEKFRWELPADYKFDREEANER

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References