Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1914463..1914608 Replicon chromosome
Accession NZ_CP119408
Organism Klebsiella pneumoniae strain NW202109

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1914499..1914601 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1914463..1914608 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P0M34_RS09325 1909593..1911653 + 2061 WP_004151449.1 oligopeptidase B -
P0M34_RS09330 1911657..1912316 - 660 WP_002911407.1 exodeoxyribonuclease X -
P0M34_RS09335 1912395..1912625 - 231 WP_002911406.1 DNA polymerase III subunit theta -
P0M34_RS09340 1912738..1913112 + 375 WP_004151448.1 CopC domain-containing protein YobA -
P0M34_RS09345 1913116..1913985 + 870 WP_040230666.1 copper homeostasis membrane protein CopD -
P0M34_RS09350 1914002..1914340 + 339 WP_016529031.1 YebY family protein -
- 1914463..1914608 - 146 - - Antitoxin
- 1914499..1914601 + 103 - - Toxin
P0M34_RS09355 1914976..1915119 - 144 WP_040230665.1 Ecr family regulatory small membrane protein -
P0M34_RS09360 1915224..1916192 - 969 WP_004151446.1 VirK/YbjX family protein -
P0M34_RS09365 1916349..1917002 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
P0M34_RS09370 1916999..1917190 - 192 WP_002911395.1 YebW family protein -
P0M34_RS09375 1917288..1917527 - 240 WP_002911393.1 YebV family protein -
P0M34_RS09380 1917643..1919077 - 1435 Protein_1830 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T274116 NZ_CP119408:1914499-1914601 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT274116 NZ_CP119408:c1914608-1914463 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References