Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/ParE-YafN |
Location | 20073..20608 | Replicon | plasmid pMRE162 NOR |
Accession | NZ_CP119401 | ||
Organism | Escherichia coli strain MRE162 substr. NOR |
Toxin (Protein)
Gene name | relE | Uniprot ID | A0A0K4CX11 |
Locus tag | PX809_RS22930 | Protein ID | WP_000222771.1 |
Coordinates | 20321..20608 (+) | Length | 96 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | T1PXV2 |
Locus tag | PX809_RS22925 | Protein ID | WP_001139206.1 |
Coordinates | 20073..20324 (+) | Length | 84 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PX809_RS22905 (PX809_004580) | 15153..15874 | + | 722 | Protein_21 | helix-turn-helix domain-containing protein | - |
PX809_RS22910 (PX809_004581) | 15913..16161 | - | 249 | WP_000747846.1 | hypothetical protein | - |
PX809_RS22915 (PX809_004582) | 16158..16598 | - | 441 | WP_023352064.1 | hypothetical protein | - |
PX809_RS22920 (PX809_004583) | 16632..19490 | - | 2859 | Protein_24 | hypothetical protein | - |
PX809_RS22925 (PX809_004584) | 20073..20324 | + | 252 | WP_001139206.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
PX809_RS22930 (PX809_004585) | 20321..20608 | + | 288 | WP_000222771.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
PX809_RS22935 (PX809_004586) | 20976..21089 | - | 114 | Protein_27 | alkaline phosphatase | - |
PX809_RS22940 (PX809_004587) | 21088..21293 | + | 206 | Protein_28 | hypothetical protein | - |
PX809_RS22945 (PX809_004588) | 21468..24965 | - | 3498 | WP_001038839.1 | autotransporter outer membrane beta-barrel domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Non-Mobilizable plasmid | - | - | 1..76850 | 76850 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0K4CX11 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | T1PXV2 |