Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | mazEF/MazF(toxin) |
Location | 490065..490702 | Replicon | chromosome |
Accession | NZ_CP119399 | ||
Organism | Bacillus velezensis strain HBXN2020 |
Toxin (Protein)
Gene name | mazF | Uniprot ID | G4NU33 |
Locus tag | P0M22_RS02505 | Protein ID | WP_003156187.1 |
Coordinates | 490352..490702 (+) | Length | 117 a.a. |
Antitoxin (Protein)
Gene name | mazE | Uniprot ID | I2HMS5 |
Locus tag | P0M22_RS02500 | Protein ID | WP_003156188.1 |
Coordinates | 490065..490346 (+) | Length | 94 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
P0M22_RS02480 (P0M22_02480) | 486430..487029 | - | 600 | WP_032872997.1 | rhomboid family intramembrane serine protease | - |
P0M22_RS02485 (P0M22_02485) | 487122..487487 | + | 366 | WP_007609580.1 | holo-ACP synthase | - |
P0M22_RS02490 (P0M22_02490) | 487652..488659 | + | 1008 | WP_032872999.1 | outer membrane lipoprotein carrier protein LolA | - |
P0M22_RS02495 (P0M22_02495) | 488776..489945 | + | 1170 | WP_032873001.1 | alanine racemase | - |
P0M22_RS02500 (P0M22_02500) | 490065..490346 | + | 282 | WP_003156188.1 | type II toxin-antitoxin system antitoxin EndoAI | Antitoxin |
P0M22_RS02505 (P0M22_02505) | 490352..490702 | + | 351 | WP_003156187.1 | type II toxin-antitoxin system endoribonuclease NdoA | Toxin |
P0M22_RS02510 (P0M22_02510) | 490820..491641 | + | 822 | WP_003156182.1 | STAS domain-containing protein | - |
P0M22_RS02515 (P0M22_02515) | 491646..492011 | + | 366 | WP_003156180.1 | RsbT antagonist protein RsbS | - |
P0M22_RS02520 (P0M22_02520) | 492014..492415 | + | 402 | WP_003156178.1 | anti-sigma regulatory factor | - |
P0M22_RS02525 (P0M22_02525) | 492427..493434 | + | 1008 | WP_007609589.1 | PP2C family protein-serine/threonine phosphatase | - |
P0M22_RS02530 (P0M22_02530) | 493498..493827 | + | 330 | WP_003156176.1 | anti-sigma factor antagonist RsbV | - |
P0M22_RS02535 (P0M22_02535) | 493824..494306 | + | 483 | WP_007609591.1 | anti-sigma B factor RsbW | - |
P0M22_RS02540 (P0M22_02540) | 494272..495060 | + | 789 | WP_032873003.1 | RNA polymerase sigma factor SigB | - |
P0M22_RS02545 (P0M22_02545) | 495060..495662 | + | 603 | WP_007410234.1 | PP2C family serine/threonine-protein phosphatase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 117 a.a. Molecular weight: 12977.98 Da Isoelectric Point: 4.8781
>T274055 WP_003156187.1 NZ_CP119399:490352-490702 [Bacillus velezensis]
MIVKRGDVYFADLSPVVGSEQGGVRPVLVIQNDIGNRFSPTAIVAAITAQIQKAKLPTHVEIDAKRYGFERDSVILLEQI
RTIDKQRLTDKITHLDDEMMDKVDEALQISLALIDF
MIVKRGDVYFADLSPVVGSEQGGVRPVLVIQNDIGNRFSPTAIVAAITAQIQKAKLPTHVEIDAKRYGFERDSVILLEQI
RTIDKQRLTDKITHLDDEMMDKVDEALQISLALIDF
Download Length: 351 bp
Antitoxin
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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