274052

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/Txe-RelB
Location 3174635..3175164 Replicon chromosome
Accession NZ_CP119393
Organism Enterococcus casseliflavus strain ASE4

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag P0G38_RS14935 Protein ID WP_087626849.1
Coordinates 3174635..3174901 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A377KQM1
Locus tag P0G38_RS14940 Protein ID WP_010748737.1
Coordinates 3174901..3175164 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P0G38_RS14920 (P0G38_14920) 3169892..3170812 + 921 WP_010748740.1 osmoprotectant ABC transporter substrate-binding protein -
P0G38_RS14925 (P0G38_14925) 3170817..3171479 + 663 WP_005227316.1 ABC transporter permease -
P0G38_RS14930 (P0G38_14930) 3171611..3174442 - 2832 WP_275852681.1 discoidin domain-containing protein -
P0G38_RS14935 (P0G38_14935) 3174635..3174901 - 267 WP_087626849.1 Txe/YoeB family addiction module toxin Toxin
P0G38_RS14940 (P0G38_14940) 3174901..3175164 - 264 WP_010748737.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
P0G38_RS14945 (P0G38_14945) 3175319..3177259 - 1941 WP_275852687.1 glycoside hydrolase family 127 protein -
P0G38_RS14950 (P0G38_14950) 3177309..3177941 - 633 WP_275852689.1 DUF624 domain-containing protein -
P0G38_RS14955 (P0G38_14955) 3177946..3178839 - 894 WP_016609627.1 carbohydrate ABC transporter permease -
P0G38_RS14960 (P0G38_14960) 3178852..3179775 - 924 WP_016609626.1 ABC transporter permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(9-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(5-69)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10612.14 Da        Isoelectric Point: 10.3322

>T274052 WP_087626849.1 NZ_CP119393:c3174901-3174635 [Enterococcus casseliflavus]
MRSDTVTIKNSAKVDLRKIKQSNLKKQFEEVIQALKEDPYMPTQSFEKLRPTHEGRYSRRLSRQHRVVYKVDEKNKVVEI
YSAWTHYE

Download         Length: 267 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9958.03 Da        Isoelectric Point: 4.2682

>AT274052 WP_010748737.1 NZ_CP119393:c3175164-3174901 [Enterococcus casseliflavus]
MAKTTMNPSTARKNFYQLLKDVNENHTEIEIISDRSGNNAVLIGLGDWRAIQETLFLEQTGTLEKVRDREKDDSGFTDID
DIDWQAL

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A377KQM1

References