Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 6021879..6022918 Replicon chromosome
Accession NZ_CP119382
Organism Pseudomonas kermanshahensis strain Mr36

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag PZ739_RS26980 Protein ID WP_275748292.1
Coordinates 6022343..6022918 (+) Length 192 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID A0A285YT07
Locus tag PZ739_RS26975 Protein ID WP_027592200.1
Coordinates 6021879..6022343 (+) Length 155 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PZ739_RS26955 (PZ739_26955) 6017099..6018430 - 1332 WP_027592203.1 ammonium transporter -
PZ739_RS26960 (PZ739_26960) 6018478..6018816 - 339 WP_002555808.1 P-II family nitrogen regulator -
PZ739_RS26965 (PZ739_26965) 6019202..6019462 + 261 WP_027592202.1 accessory factor UbiK family protein -
PZ739_RS26970 (PZ739_26970) 6019466..6021493 - 2028 WP_275748289.1 DUF4034 domain-containing protein -
PZ739_RS26975 (PZ739_26975) 6021879..6022343 + 465 WP_027592200.1 helix-turn-helix domain-containing protein Antitoxin
PZ739_RS26980 (PZ739_26980) 6022343..6022918 + 576 WP_275748292.1 PIN domain-containing protein Toxin
PZ739_RS26985 (PZ739_26985) 6023077..6024564 + 1488 WP_275748294.1 YifB family Mg chelatase-like AAA ATPase -
PZ739_RS26990 (PZ739_26990) 6024666..6025019 - 354 WP_027592197.1 response regulator -
PZ739_RS26995 (PZ739_26995) 6025049..6026041 - 993 WP_275748296.1 response regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(8-115)

Antitoxin

SinI-like, DNA-binding domain

(84-130)


Sequences

Toxin        


Download         Length: 192 a.a.        Molecular weight: 21936.36 Da        Isoelectric Point: 5.5558

>T274049 WP_275748292.1 NZ_CP119382:6022343-6022918 [Pseudomonas kermanshahensis]
MRHSPFTVIYDACVLYPAPLRDLLMHLALTGVFRARWSEQIHDEWTRNVLKNRPDVSPTQLHRTVAFMNQAIPDSLVSDY
EPLIHGLDLPDEDDRHVLAAAIKCGATVIVTYNLKDFPSEILKRFEIEALHPDVFLSDIWDLDQAAVLEAVQKQRAALKN
PVYTPRELMDSLLKQRLPEIVKLLSNYELLI

Download         Length: 576 bp

Antitoxin


Download         Length: 155 a.a.        Molecular weight: 16926.27 Da        Isoelectric Point: 5.6386

>AT274049 WP_027592200.1 NZ_CP119382:6021879-6022343 [Pseudomonas kermanshahensis]
MTTADFARTILPDEKAIAAATESSRQIAAFVSTKLDTQRIELVDENQQRQTVELPTFALRLLGDILNELASGNTVKVVPI
HAELTTQEGADLLNVSRPHLVKLLDEGLIPHTKTGSHRRIKFTDLMAYKADRDKASQAAMEELAAQAQALNMGY

Download         Length: 465 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A285YT07

References