274048

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 1048558..1049242 Replicon chromosome
Accession NZ_CP119382
Organism Pseudomonas kermanshahensis strain Mr36

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag PZ739_RS04685 Protein ID WP_275749295.1
Coordinates 1048871..1049242 (-) Length 124 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag PZ739_RS04680 Protein ID WP_238210372.1
Coordinates 1048558..1048878 (-) Length 107 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PZ739_RS04655 (PZ739_04655) 1044723..1045124 + 402 WP_027595598.1 hypothetical protein -
PZ739_RS04660 (PZ739_04660) 1045117..1046493 + 1377 WP_275749287.1 class II fumarate hydratase -
PZ739_RS04665 (PZ739_04665) 1046543..1047004 + 462 WP_027595600.1 hypothetical protein -
PZ739_RS04670 (PZ739_04670) 1047006..1047617 + 612 WP_275749290.1 superoxide dismutase -
PZ739_RS04675 (PZ739_04675) 1047629..1048522 + 894 WP_275749292.1 ZIP family metal transporter -
PZ739_RS04680 (PZ739_04680) 1048558..1048878 - 321 WP_238210372.1 helix-turn-helix transcriptional regulator Antitoxin
PZ739_RS04685 (PZ739_04685) 1048871..1049242 - 372 WP_275749295.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PZ739_RS04690 (PZ739_04690) 1049330..1049602 - 273 WP_027595603.1 HPr family phosphocarrier protein -
PZ739_RS04695 (PZ739_04695) 1049623..1050477 - 855 WP_275749298.1 RNase adapter RapZ -
PZ739_RS04700 (PZ739_04700) 1050480..1050944 - 465 WP_275749299.1 PTS IIA-like nitrogen regulatory protein PtsN -
PZ739_RS04705 (PZ739_04705) 1050957..1051265 - 309 WP_003255135.1 ribosome-associated translation inhibitor RaiA -
PZ739_RS04710 (PZ739_04710) 1051345..1052838 - 1494 WP_027595606.1 RNA polymerase factor sigma-54 -
PZ739_RS04715 (PZ739_04715) 1053014..1053739 - 726 WP_027595607.1 LPS export ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(18-111)

Antitoxin

HigA2-like, helix-turn-helix domain

(11-90)


Sequences

Toxin        


Download         Length: 124 a.a.        Molecular weight: 13508.46 Da        Isoelectric Point: 9.1022

>T274048 WP_275749295.1 NZ_CP119382:c1049242-1048871 [Pseudomonas kermanshahensis]
MDAFKRVKPLYWVGSCKKDLQEAPSDVQDIFGFALHLAQEGGKHPQAKCLKGFTGAGVLEVVENHDSDTYRAIYTVSLGA
AVYVLHCFQKKSNSGIKTPKHDLDLVKSRLKQAVAHAKGTTHD

Download         Length: 372 bp

Antitoxin


Download         Length: 107 a.a.        Molecular weight: 11605.65 Da        Isoelectric Point: 9.8520

>AT274048 WP_238210372.1 NZ_CP119382:c1048878-1048558 [Pseudomonas kermanshahensis]
MIEIEESSGNVYADLNSADAGEMLIKAHLASKICSIIKARHLTQVQAAAVLGLPQPKVSEMMRGKFRGISETKMIDCLAR
LGRDIQIVVKAAPRSRREGRVEVIFA

Download         Length: 321 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References