274046

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 619998..621712 Replicon chromosome
Accession NZ_CP119382
Organism Pseudomonas kermanshahensis strain Mr36

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag PZ739_RS02790 Protein ID WP_275748766.1
Coordinates 621068..621712 (-) Length 215 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag PZ739_RS02785 Protein ID WP_275748765.1
Coordinates 619998..621071 (-) Length 358 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PZ739_RS02755 (PZ739_02755) 615155..616042 - 888 WP_275748763.1 (2E,6E)-farnesyl diphosphate synthase -
PZ739_RS02760 (PZ739_02760) 616039..616281 - 243 WP_027594918.1 exodeoxyribonuclease VII small subunit -
PZ739_RS02765 (PZ739_02765) 616468..617118 - 651 WP_186703991.1 3,4-dihydroxy-2-butanone-4-phosphate synthase -
PZ739_RS02770 (PZ739_02770) 617435..618649 + 1215 WP_275751891.1 RtcB family protein -
PZ739_RS02775 (PZ739_02775) 618757..619653 - 897 WP_275748764.1 alpha/beta hydrolase -
PZ739_RS02780 (PZ739_02780) 619702..620024 + 323 Protein_534 hypothetical protein -
PZ739_RS02785 (PZ739_02785) 619998..621071 - 1074 WP_275748765.1 macro domain-containing protein Antitoxin
PZ739_RS02790 (PZ739_02790) 621068..621712 - 645 WP_275748766.1 DUF4433 domain-containing protein Toxin
PZ739_RS02795 (PZ739_02795) 621713..622291 - 579 WP_275748767.1 DarT ssDNA thymidine ADP-ribosyltransferase family protein -
PZ739_RS02800 (PZ739_02800) 622742..623443 - 702 WP_275748768.1 XRE family transcriptional regulator -
PZ739_RS02805 (PZ739_02805) 623622..624149 - 528 WP_016497835.1 inorganic diphosphatase -
PZ739_RS02810 (PZ739_02810) 624242..625057 - 816 WP_275748769.1 zinc-dependent peptidase -
PZ739_RS02815 (PZ739_02815) 625066..625713 - 648 WP_027594930.1 DedA family protein -
PZ739_RS02820 (PZ739_02820) 625902..626360 - 459 WP_275748770.1 GNAT family N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(14-213)

Antitoxin

Macro domain

(18-130)


Sequences

Toxin        


Download         Length: 215 a.a.        Molecular weight: 24516.06 Da        Isoelectric Point: 7.1463

>T274046 WP_275748766.1 NZ_CP119382:c621712-621068 [Pseudomonas kermanshahensis]
MSYSRLNPDKALIWRIVHRDALPWILDNGLHCENSGVQATQCVNIDNAELIDKRRSRQVPIAPGGVLADYVPFCFTPFSV
MMRNIHAGWSVQQRSNDEIVILVSSLYRVQALGLPFVFTNALAYPAWTSYYSDLAYLGEVDWPLLQRRNFTRDPDDPRKV
ERYQAEALIHHHLPITGLLGIMCYNDAIKERIEHDVAARGLSLPVHARPGWYFQ

Download         Length: 645 bp

Antitoxin


Download         Length: 358 a.a.        Molecular weight: 40193.29 Da        Isoelectric Point: 7.0991

>AT274046 WP_275748765.1 NZ_CP119382:c621071-619998 [Pseudomonas kermanshahensis]
MIRFTQGNLLEAKTEALVNTVNTVGVMGKGIALMFKERFVENYRLYAAACKAGEVVTGKVHVTAVNELEGPQWIVNFPTK
RHWRSPSQMAWVTEGLHDLRRFLIENHVKSVAVPALGAGNGGLKWPEVREQIIHVLSDLNVDIWVYEPSSQYLNVAKRSG
VKTLTPARALIAELVRRYWVLGMECSLLEIQKLAWFLERAIEKLPDTENPLNLKFVAHRYGPYANRLQHLLHDLDGSYLH
CEKRIKDAELGDVIWFEEKRKPTLHTYLDTEAKAYSQALERTIELIDGFESPFGMELLATVDWLLSHEGVCPTVPAVRDA
LTHWEGGAGSAARKSKLFDDQALDIALKRLTASTALG

Download         Length: 1074 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References