Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 3747643..3748863 Replicon chromosome
Accession NZ_CP119371
Organism Pseudomonas sp. CBSPCAW29

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag P0D95_RS17350 Protein ID WP_258344820.1
Coordinates 3747643..3748218 (-) Length 192 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag P0D95_RS17355 Protein ID WP_258344821.1
Coordinates 3748306..3748863 (-) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P0D95_RS17330 (P0D95_17330) 3743279..3744319 + 1041 WP_177027103.1 PilN domain-containing protein -
P0D95_RS17335 (P0D95_17335) 3744294..3744905 + 612 WP_258344817.1 type II secretion system protein GspM -
P0D95_RS17340 (P0D95_17340) 3744902..3745426 + 525 WP_258344818.1 DUF2531 family protein -
P0D95_RS17345 (P0D95_17345) 3745423..3747636 + 2214 WP_258344819.1 type II secretion system secretin GspD -
P0D95_RS17350 (P0D95_17350) 3747643..3748218 - 576 WP_258344820.1 HD domain-containing protein Toxin
P0D95_RS17355 (P0D95_17355) 3748306..3748863 - 558 WP_258344821.1 helix-turn-helix transcriptional regulator Antitoxin
P0D95_RS17360 (P0D95_17360) 3748961..3749623 - 663 WP_258344822.1 RraA family protein -
P0D95_RS17365 (P0D95_17365) 3749649..3750986 - 1338 WP_256576936.1 MFS transporter -
P0D95_RS17370 (P0D95_17370) 3751071..3752312 - 1242 WP_275708835.1 pyridoxal phosphate-dependent aminotransferase -
P0D95_RS17375 (P0D95_17375) 3752309..3752965 - 657 WP_258344824.1 RraA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HD domain

(16-173)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-46)


Sequences

Toxin        


Download         Length: 192 a.a.        Molecular weight: 21642.58 Da        Isoelectric Point: 4.9800

>T274043 WP_258344820.1 NZ_CP119371:c3748218-3747643 [Pseudomonas sp. CBSPCAW29]
MDIEKLKGRLDFLREAEKLKDVLRSAHTSSGRTESTAEHSWRLCLMAITFGDELAGLDLLKILKMCVIHDLGEALHGDIP
AVQQAQFPNKSQQEHDDLLLLTRALDEPLRVEILALWDDYENARSAEAKAVKALDKLETLLQHNQGLNPPDFDYAFNLAY
GKKHTSAEPIFQTLREIIDQDTEAKIQTPNR

Download         Length: 576 bp

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 20596.80 Da        Isoelectric Point: 7.8767

>AT274043 WP_258344821.1 NZ_CP119371:c3748863-3748306 [Pseudomonas sp. CBSPCAW29]
MSDLLLKPALPGIALRRWRLLHRVKQTHAAELFHVTQSTISRWESGVQAMEPAAHRQLEQLLAARLEAAADQALARLVKE
SPRPMHLVCDLTHRLLACSASRAAEFSSPLAELLGHSLWRFVTPEILRMESALDDSGWRDSLAPPALEFITGTNDSTVVP
IRQSLCRWTRIPLSDGTAARLVETL

Download         Length: 558 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References