Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 876994..877510 Replicon chromosome
Accession NZ_CP119371
Organism Pseudomonas sp. CBSPCAW29

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag P0D95_RS04205 Protein ID WP_258342669.1
Coordinates 876994..877281 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag P0D95_RS04210 Protein ID WP_258348672.1
Coordinates 877271..877510 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P0D95_RS04185 (P0D95_04185) 872576..873523 - 948 WP_177020250.1 FecR family protein -
P0D95_RS04190 (P0D95_04190) 873582..874055 - 474 WP_275845531.1 RNA polymerase sigma factor -
P0D95_RS04195 (P0D95_04195) 874267..875325 - 1059 WP_256344485.1 haloacid dehalogenase-like hydrolase -
P0D95_RS04200 (P0D95_04200) 875567..876958 + 1392 WP_258342668.1 L-cystine transporter -
P0D95_RS04205 (P0D95_04205) 876994..877281 - 288 WP_258342669.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
P0D95_RS04210 (P0D95_04210) 877271..877510 - 240 WP_258348672.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
P0D95_RS04215 (P0D95_04215) 877594..878082 - 489 WP_275845630.1 dihydrofolate reductase -
P0D95_RS04220 (P0D95_04220) 878196..879575 + 1380 WP_258342670.1 DUF2868 domain-containing protein -
P0D95_RS04225 (P0D95_04225) 879568..880941 + 1374 WP_258342671.1 DUF3482 domain-containing protein -
P0D95_RS04230 (P0D95_04230) 880938..881492 - 555 WP_258342672.1 HD domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-81)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-64)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11365.24 Da        Isoelectric Point: 10.0977

>T274042 WP_258342669.1 NZ_CP119371:c877281-876994 [Pseudomonas sp. CBSPCAW29]
MTYNLEFDARALKEWRKLGDTVRQQLKKKLVEILTHPRIEANRLHGLPDCYKIKLRSSGYRLVYQVIDQEVMVFVVAVDK
RERDEVYRKATERLS

Download         Length: 288 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8963.34 Da        Isoelectric Point: 4.7962

>AT274042 WP_258348672.1 NZ_CP119371:c877510-877271 [Pseudomonas sp. CBSPCAW29]
MASINIRIDDDLKARAYHELEKLGVTPSELMRQALQYVAERGQLPFKPVLMTEDDEALLATVRERLAAPQRVKVSLDDL

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References