Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 7145797..7147017 Replicon chromosome
Accession NZ_CP119370
Organism Pseudomonas sp. CBSPCBW29

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag P0D90_RS33080 Protein ID WP_258344820.1
Coordinates 7145797..7146372 (-) Length 192 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag P0D90_RS33085 Protein ID WP_258344821.1
Coordinates 7146460..7147017 (-) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P0D90_RS33060 (P0D90_33060) 7141434..7142474 + 1041 WP_177027103.1 PilN domain-containing protein -
P0D90_RS33065 (P0D90_33065) 7142449..7143060 + 612 WP_258344817.1 type II secretion system protein GspM -
P0D90_RS33070 (P0D90_33070) 7143057..7143580 + 524 Protein_6528 general secretion pathway protein GspN -
P0D90_RS33075 (P0D90_33075) 7143577..7145790 + 2214 WP_258344819.1 type II secretion system secretin GspD -
P0D90_RS33080 (P0D90_33080) 7145797..7146372 - 576 WP_258344820.1 HD domain-containing protein Toxin
P0D90_RS33085 (P0D90_33085) 7146460..7147017 - 558 WP_258344821.1 helix-turn-helix transcriptional regulator Antitoxin
P0D90_RS33090 (P0D90_33090) 7147115..7147777 - 663 WP_258344822.1 RraA family protein -
P0D90_RS33095 (P0D90_33095) 7147803..7149139 - 1337 Protein_6533 MFS transporter -
P0D90_RS33100 (P0D90_33100) 7149224..7150465 - 1242 WP_275708835.1 pyridoxal phosphate-dependent aminotransferase -
P0D90_RS33105 (P0D90_33105) 7150462..7151118 - 657 WP_258344824.1 RraA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HD domain

(16-173)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-46)


Sequences

Toxin        


Download         Length: 192 a.a.        Molecular weight: 21642.58 Da        Isoelectric Point: 4.9800

>T274041 WP_258344820.1 NZ_CP119370:c7146372-7145797 [Pseudomonas sp. CBSPCBW29]
MDIEKLKGRLDFLREAEKLKDVLRSAHTSSGRTESTAEHSWRLCLMAITFGDELAGLDLLKILKMCVIHDLGEALHGDIP
AVQQAQFPNKSQQEHDDLLLLTRALDEPLRVEILALWDDYENARSAEAKAVKALDKLETLLQHNQGLNPPDFDYAFNLAY
GKKHTSAEPIFQTLREIIDQDTEAKIQTPNR

Download         Length: 576 bp

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 20596.80 Da        Isoelectric Point: 7.8767

>AT274041 WP_258344821.1 NZ_CP119370:c7147017-7146460 [Pseudomonas sp. CBSPCBW29]
MSDLLLKPALPGIALRRWRLLHRVKQTHAAELFHVTQSTISRWESGVQAMEPAAHRQLEQLLAARLEAAADQALARLVKE
SPRPMHLVCDLTHRLLACSASRAAEFSSPLAELLGHSLWRFVTPEILRMESALDDSGWRDSLAPPALEFITGTNDSTVVP
IRQSLCRWTRIPLSDGTAARLVETL

Download         Length: 558 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References