Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 4275278..4275794 Replicon chromosome
Accession NZ_CP119370
Organism Pseudomonas sp. CBSPCBW29

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag P0D90_RS19890 Protein ID WP_258342669.1
Coordinates 4275278..4275565 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag P0D90_RS19895 Protein ID WP_258348672.1
Coordinates 4275555..4275794 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P0D90_RS19865 (P0D90_19865) 4270864..4271811 - 948 WP_177020250.1 FecR family protein -
P0D90_RS19870 (P0D90_19870) 4271870..4272139 - 270 WP_275712766.1 sigma-70 family RNA polymerase sigma factor -
P0D90_RS19875 (P0D90_19875) 4272187..4272246 - 60 Protein_3930 RNA polymerase subunit sigma -
P0D90_RS19880 (P0D90_19880) 4272551..4273609 - 1059 WP_256344485.1 haloacid dehalogenase-like hydrolase -
P0D90_RS19885 (P0D90_19885) 4273851..4275242 + 1392 WP_258342668.1 L-cystine transporter -
P0D90_RS19890 (P0D90_19890) 4275278..4275565 - 288 WP_258342669.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
P0D90_RS19895 (P0D90_19895) 4275555..4275794 - 240 WP_258348672.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
P0D90_RS19900 (P0D90_19900) 4275878..4276390 - 513 WP_008438965.1 dihydrofolate reductase -
P0D90_RS19905 (P0D90_19905) 4276481..4277860 + 1380 WP_258342670.1 DUF2868 domain-containing protein -
P0D90_RS19910 (P0D90_19910) 4277853..4279226 + 1374 WP_258342671.1 DUF3482 domain-containing protein -
P0D90_RS19915 (P0D90_19915) 4279223..4279776 - 554 Protein_3938 HD domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-81)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-64)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11365.24 Da        Isoelectric Point: 10.0977

>T274040 WP_258342669.1 NZ_CP119370:c4275565-4275278 [Pseudomonas sp. CBSPCBW29]
MTYNLEFDARALKEWRKLGDTVRQQLKKKLVEILTHPRIEANRLHGLPDCYKIKLRSSGYRLVYQVIDQEVMVFVVAVDK
RERDEVYRKATERLS

Download         Length: 288 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8963.34 Da        Isoelectric Point: 4.7962

>AT274040 WP_258348672.1 NZ_CP119370:c4275794-4275555 [Pseudomonas sp. CBSPCBW29]
MASINIRIDDDLKARAYHELEKLGVTPSELMRQALQYVAERGQLPFKPVLMTEDDEALLATVRERLAAPQRVKVSLDDL

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References