Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 6192088..6193308 Replicon chromosome
Accession NZ_CP119369
Organism Pseudomonas sp. CBSPAW29

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag P0D92_RS28460 Protein ID WP_258344820.1
Coordinates 6192733..6193308 (+) Length 192 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag P0D92_RS28455 Protein ID WP_258344821.1
Coordinates 6192088..6192645 (+) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P0D92_RS28435 (P0D92_28435) 6187986..6188642 + 657 WP_258344824.1 RraA family protein -
P0D92_RS28440 (P0D92_28440) 6188639..6189880 + 1242 WP_275708835.1 pyridoxal phosphate-dependent aminotransferase -
P0D92_RS28445 (P0D92_28445) 6189965..6191302 + 1338 WP_256576936.1 MFS transporter -
P0D92_RS28450 (P0D92_28450) 6191328..6191990 + 663 WP_258344822.1 RraA family protein -
P0D92_RS28455 (P0D92_28455) 6192088..6192645 + 558 WP_258344821.1 helix-turn-helix transcriptional regulator Antitoxin
P0D92_RS28460 (P0D92_28460) 6192733..6193308 + 576 WP_258344820.1 HD domain-containing protein Toxin
P0D92_RS28465 (P0D92_28465) 6193315..6195528 - 2214 WP_258344819.1 type II secretion system secretin GspD -
P0D92_RS28470 (P0D92_28470) 6195525..6196049 - 525 WP_258344818.1 DUF2531 family protein -
P0D92_RS28475 (P0D92_28475) 6196046..6196657 - 612 WP_258344817.1 type II secretion system protein GspM -
P0D92_RS28480 (P0D92_28480) 6196632..6197671 - 1040 Protein_5622 PilN domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HD domain

(16-173)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-46)


Sequences

Toxin        


Download         Length: 192 a.a.        Molecular weight: 21642.58 Da        Isoelectric Point: 4.9800

>T274037 WP_258344820.1 NZ_CP119369:6192733-6193308 [Pseudomonas sp. CBSPAW29]
MDIEKLKGRLDFLREAEKLKDVLRSAHTSSGRTESTAEHSWRLCLMAITFGDELAGLDLLKILKMCVIHDLGEALHGDIP
AVQQAQFPNKSQQEHDDLLLLTRALDEPLRVEILALWDDYENARSAEAKAVKALDKLETLLQHNQGLNPPDFDYAFNLAY
GKKHTSAEPIFQTLREIIDQDTEAKIQTPNR

Download         Length: 576 bp

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 20596.80 Da        Isoelectric Point: 7.8767

>AT274037 WP_258344821.1 NZ_CP119369:6192088-6192645 [Pseudomonas sp. CBSPAW29]
MSDLLLKPALPGIALRRWRLLHRVKQTHAAELFHVTQSTISRWESGVQAMEPAAHRQLEQLLAARLEAAADQALARLVKE
SPRPMHLVCDLTHRLLACSASRAAEFSSPLAELLGHSLWRFVTPEILRMESALDDSGWRDSLAPPALEFITGTNDSTVVP
IRQSLCRWTRIPLSDGTAARLVETL

Download         Length: 558 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References