Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 1819751..1820267 Replicon chromosome
Accession NZ_CP119369
Organism Pseudomonas sp. CBSPAW29

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag P0D92_RS08195 Protein ID WP_258342669.1
Coordinates 1819980..1820267 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag P0D92_RS08190 Protein ID WP_258348672.1
Coordinates 1819751..1819990 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P0D92_RS08170 (P0D92_08170) 1815769..1816323 + 555 WP_258342672.1 HD domain-containing protein -
P0D92_RS08175 (P0D92_08175) 1816320..1817693 - 1374 WP_258342671.1 DUF3482 domain-containing protein -
P0D92_RS08180 (P0D92_08180) 1817686..1819064 - 1379 Protein_1607 DUF2868 domain-containing protein -
P0D92_RS08185 (P0D92_08185) 1819155..1819667 + 513 WP_008438965.1 dihydrofolate reductase -
P0D92_RS08190 (P0D92_08190) 1819751..1819990 + 240 WP_258348672.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
P0D92_RS08195 (P0D92_08195) 1819980..1820267 + 288 WP_258342669.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
P0D92_RS08200 (P0D92_08200) 1820303..1821693 - 1391 Protein_1611 L-cystine transporter -
P0D92_RS08205 (P0D92_08205) 1821935..1822993 + 1059 WP_256344485.1 haloacid dehalogenase-like hydrolase -
P0D92_RS08210 (P0D92_08210) 1823205..1823738 + 534 WP_177020251.1 RNA polymerase sigma factor -
P0D92_RS08215 (P0D92_08215) 1823735..1824682 + 948 WP_177020250.1 FecR family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - algC / algC / algR / pilT / pilG / pilH / pilI / pilJ 1601604..1899809 298205


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-81)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-64)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11365.24 Da        Isoelectric Point: 10.0977

>T274034 WP_258342669.1 NZ_CP119369:1819980-1820267 [Pseudomonas sp. CBSPAW29]
MTYNLEFDARALKEWRKLGDTVRQQLKKKLVEILTHPRIEANRLHGLPDCYKIKLRSSGYRLVYQVIDQEVMVFVVAVDK
RERDEVYRKATERLS

Download         Length: 288 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8963.34 Da        Isoelectric Point: 4.7962

>AT274034 WP_258348672.1 NZ_CP119369:1819751-1819990 [Pseudomonas sp. CBSPAW29]
MASINIRIDDDLKARAYHELEKLGVTPSELMRQALQYVAERGQLPFKPVLMTEDDEALLATVRERLAAPQRVKVSLDDL

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References