Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 4837970..4839190 Replicon chromosome
Accession NZ_CP119368
Organism Pseudomonas sp. CBSPCGW29

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag P0D94_RS22395 Protein ID WP_258344820.1
Coordinates 4838615..4839190 (+) Length 192 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag P0D94_RS22390 Protein ID WP_258344821.1
Coordinates 4837970..4838527 (+) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P0D94_RS22370 (P0D94_22370) 4833868..4834524 + 657 WP_258344824.1 RraA family protein -
P0D94_RS22375 (P0D94_22375) 4834521..4835762 + 1242 WP_275708835.1 pyridoxal phosphate-dependent aminotransferase -
P0D94_RS22380 (P0D94_22380) 4835847..4837184 + 1338 WP_256576936.1 MFS transporter -
P0D94_RS22385 (P0D94_22385) 4837210..4837872 + 663 WP_258344822.1 RraA family protein -
P0D94_RS22390 (P0D94_22390) 4837970..4838527 + 558 WP_258344821.1 helix-turn-helix transcriptional regulator Antitoxin
P0D94_RS22395 (P0D94_22395) 4838615..4839190 + 576 WP_258344820.1 HD domain-containing protein Toxin
P0D94_RS22400 (P0D94_22400) 4839197..4841410 - 2214 WP_258344819.1 type II secretion system secretin GspD -
P0D94_RS22405 (P0D94_22405) 4841407..4841931 - 525 WP_258344818.1 DUF2531 family protein -
P0D94_RS22410 (P0D94_22410) 4841928..4842539 - 612 WP_258344817.1 type II secretion system protein GspM -
P0D94_RS22415 (P0D94_22415) 4842514..4843554 - 1041 WP_177027103.1 PilN domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HD domain

(16-173)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-46)


Sequences

Toxin        


Download         Length: 192 a.a.        Molecular weight: 21642.58 Da        Isoelectric Point: 4.9800

>T274033 WP_258344820.1 NZ_CP119368:4838615-4839190 [Pseudomonas sp. CBSPCGW29]
MDIEKLKGRLDFLREAEKLKDVLRSAHTSSGRTESTAEHSWRLCLMAITFGDELAGLDLLKILKMCVIHDLGEALHGDIP
AVQQAQFPNKSQQEHDDLLLLTRALDEPLRVEILALWDDYENARSAEAKAVKALDKLETLLQHNQGLNPPDFDYAFNLAY
GKKHTSAEPIFQTLREIIDQDTEAKIQTPNR

Download         Length: 576 bp

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 20596.80 Da        Isoelectric Point: 7.8767

>AT274033 WP_258344821.1 NZ_CP119368:4837970-4838527 [Pseudomonas sp. CBSPCGW29]
MSDLLLKPALPGIALRRWRLLHRVKQTHAAELFHVTQSTISRWESGVQAMEPAAHRQLEQLLAARLEAAADQALARLVKE
SPRPMHLVCDLTHRLLACSASRAAEFSSPLAELLGHSLWRFVTPEILRMESALDDSGWRDSLAPPALEFITGTNDSTVVP
IRQSLCRWTRIPLSDGTAARLVETL

Download         Length: 558 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References