Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/HicA(toxin)
Location 2320995..2321599 Replicon chromosome
Accession NZ_CP119368
Organism Pseudomonas sp. CBSPCGW29

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag P0D94_RS11075 Protein ID WP_258346945.1
Coordinates 2321348..2321599 (-) Length 84 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag P0D94_RS11070 Protein ID WP_258346946.1
Coordinates 2320995..2321351 (-) Length 119 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P0D94_RS11055 (P0D94_11055) 2316681..2318188 + 1508 Protein_2172 MDR family MFS transporter -
P0D94_RS11060 (P0D94_11060) 2319102..2319686 - 585 WP_258346948.1 TetR/AcrR family transcriptional regulator -
P0D94_RS11065 (P0D94_11065) 2319822..2320994 + 1173 WP_258346947.1 MFS transporter -
P0D94_RS11070 (P0D94_11070) 2320995..2321351 - 357 WP_258346946.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
P0D94_RS11075 (P0D94_11075) 2321348..2321599 - 252 WP_258346945.1 type II toxin-antitoxin system HicA family toxin Toxin
P0D94_RS11080 (P0D94_11080) 2321789..2322772 + 984 WP_258346944.1 TauD/TfdA family dioxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(20-76)

Antitoxin

Uncharacterised protein family HicB

(55-105)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9509.99 Da        Isoelectric Point: 10.3760

>T274032 WP_258346945.1 NZ_CP119368:c2321599-2321348 [Pseudomonas sp. CBSPCGW29]
VSKNEKLLAKLLNEQSAFTWAERVTLLRRLGYTQIEGAGSRVRFDIGDPSAMITLHKPHPGNELKHYIRRQIIEQLKSGE
LIQ

Download         Length: 252 bp

Antitoxin


Download         Length: 119 a.a.        Molecular weight: 12821.70 Da        Isoelectric Point: 6.8428

>AT274032 WP_258346946.1 NZ_CP119368:c2321351-2320995 [Pseudomonas sp. CBSPCGW29]
VNNQLKHKGYIGSIEASLEDNCLFGKLLFIKALVSYEGKTVAELDTAFCTAVDDYIETCMALGQTPEKPCKGSFNVRVGH
DLHLAAALAATRQKVTLNDLTRQALNEFLQHRGALVAG

Download         Length: 357 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References