Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 472038..472554 Replicon chromosome
Accession NZ_CP119368
Organism Pseudomonas sp. CBSPCGW29

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag P0D94_RS02215 Protein ID WP_258342669.1
Coordinates 472267..472554 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag P0D94_RS02210 Protein ID WP_258348672.1
Coordinates 472038..472277 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P0D94_RS02190 (P0D94_02190) 468056..468610 + 555 WP_258342672.1 HD domain-containing protein -
P0D94_RS02195 (P0D94_02195) 468607..469979 - 1373 Protein_437 DUF3482 domain-containing protein -
P0D94_RS02200 (P0D94_02200) 469972..471351 - 1380 WP_258342670.1 DUF2868 domain-containing protein -
P0D94_RS02205 (P0D94_02205) 471442..471954 + 513 WP_008438965.1 dihydrofolate reductase -
P0D94_RS02210 (P0D94_02210) 472038..472277 + 240 WP_258348672.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
P0D94_RS02215 (P0D94_02215) 472267..472554 + 288 WP_258342669.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
P0D94_RS02220 (P0D94_02220) 472590..473981 - 1392 WP_258342668.1 L-cystine transporter -
P0D94_RS02225 (P0D94_02225) 474223..475281 + 1059 WP_256344485.1 haloacid dehalogenase-like hydrolase -
P0D94_RS02230 (P0D94_02230) 475493..476026 + 534 WP_177020251.1 RNA polymerase sigma factor -
P0D94_RS02235 (P0D94_02235) 476023..476970 + 948 WP_177020250.1 FecR family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-81)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-64)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11365.24 Da        Isoelectric Point: 10.0977

>T274030 WP_258342669.1 NZ_CP119368:472267-472554 [Pseudomonas sp. CBSPCGW29]
MTYNLEFDARALKEWRKLGDTVRQQLKKKLVEILTHPRIEANRLHGLPDCYKIKLRSSGYRLVYQVIDQEVMVFVVAVDK
RERDEVYRKATERLS

Download         Length: 288 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8963.34 Da        Isoelectric Point: 4.7962

>AT274030 WP_258348672.1 NZ_CP119368:472038-472277 [Pseudomonas sp. CBSPCGW29]
MASINIRIDDDLKARAYHELEKLGVTPSELMRQALQYVAERGQLPFKPVLMTEDDEALLATVRERLAAPQRVKVSLDDL

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References