Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 678209..679429 Replicon chromosome
Accession NZ_CP119367
Organism Pseudomonas sp. CBSPGW29

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag P0D93_RS03060 Protein ID WP_258344820.1
Coordinates 678854..679429 (+) Length 192 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag P0D93_RS03055 Protein ID WP_258344821.1
Coordinates 678209..678766 (+) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P0D93_RS03035 (P0D93_03035) 674107..674763 + 657 WP_258344824.1 RraA family protein -
P0D93_RS03040 (P0D93_03040) 674760..676001 + 1242 WP_275708835.1 pyridoxal phosphate-dependent aminotransferase -
P0D93_RS03045 (P0D93_03045) 676086..677423 + 1338 WP_256576936.1 MFS transporter -
P0D93_RS03050 (P0D93_03050) 677449..678111 + 663 WP_258344822.1 RraA family protein -
P0D93_RS03055 (P0D93_03055) 678209..678766 + 558 WP_258344821.1 helix-turn-helix transcriptional regulator Antitoxin
P0D93_RS03060 (P0D93_03060) 678854..679429 + 576 WP_258344820.1 HD domain-containing protein Toxin
P0D93_RS03065 (P0D93_03065) 679436..681649 - 2214 WP_258344819.1 type II secretion system secretin GspD -
P0D93_RS03070 (P0D93_03070) 681646..682170 - 525 WP_258344818.1 DUF2531 family protein -
P0D93_RS03075 (P0D93_03075) 682167..682778 - 612 WP_258344817.1 type II secretion system protein GspM -
P0D93_RS03080 (P0D93_03080) 682753..683793 - 1041 WP_177027103.1 PilN domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HD domain

(16-173)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-46)


Sequences

Toxin        


Download         Length: 192 a.a.        Molecular weight: 21642.58 Da        Isoelectric Point: 4.9800

>T274026 WP_258344820.1 NZ_CP119367:678854-679429 [Pseudomonas sp. CBSPGW29]
MDIEKLKGRLDFLREAEKLKDVLRSAHTSSGRTESTAEHSWRLCLMAITFGDELAGLDLLKILKMCVIHDLGEALHGDIP
AVQQAQFPNKSQQEHDDLLLLTRALDEPLRVEILALWDDYENARSAEAKAVKALDKLETLLQHNQGLNPPDFDYAFNLAY
GKKHTSAEPIFQTLREIIDQDTEAKIQTPNR

Download         Length: 576 bp

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 20596.80 Da        Isoelectric Point: 7.8767

>AT274026 WP_258344821.1 NZ_CP119367:678209-678766 [Pseudomonas sp. CBSPGW29]
MSDLLLKPALPGIALRRWRLLHRVKQTHAAELFHVTQSTISRWESGVQAMEPAAHRQLEQLLAARLEAAADQALARLVKE
SPRPMHLVCDLTHRLLACSASRAAEFSSPLAELLGHSLWRFVTPEILRMESALDDSGWRDSLAPPALEFITGTNDSTVVP
IRQSLCRWTRIPLSDGTAARLVETL

Download         Length: 558 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References