Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 4820210..4820726 Replicon chromosome
Accession NZ_CP119366
Organism Pseudomonas sp. CBSPBW29

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag P0D91_RS22105 Protein ID WP_258342669.1
Coordinates 4820439..4820726 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag P0D91_RS22100 Protein ID WP_258348672.1
Coordinates 4820210..4820449 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P0D91_RS22080 (P0D91_22080) 4816227..4816781 + 555 WP_258342672.1 HD domain-containing protein -
P0D91_RS22085 (P0D91_22085) 4816778..4818151 - 1374 WP_258342671.1 DUF3482 domain-containing protein -
P0D91_RS22090 (P0D91_22090) 4818144..4819523 - 1380 WP_258342670.1 DUF2868 domain-containing protein -
P0D91_RS22095 (P0D91_22095) 4819614..4820126 + 513 WP_008438965.1 dihydrofolate reductase -
P0D91_RS22100 (P0D91_22100) 4820210..4820449 + 240 WP_258348672.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
P0D91_RS22105 (P0D91_22105) 4820439..4820726 + 288 WP_258342669.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
P0D91_RS22110 (P0D91_22110) 4820762..4822153 - 1392 WP_258342668.1 L-cystine transporter -
P0D91_RS22115 (P0D91_22115) 4822395..4823453 + 1059 WP_256344485.1 haloacid dehalogenase-like hydrolase -
P0D91_RS22120 (P0D91_22120) 4823665..4824198 + 534 WP_177020251.1 RNA polymerase sigma factor -
P0D91_RS22125 (P0D91_22125) 4824195..4825142 + 948 WP_177020250.1 FecR family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-81)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-64)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11365.24 Da        Isoelectric Point: 10.0977

>T274023 WP_258342669.1 NZ_CP119366:4820439-4820726 [Pseudomonas sp. CBSPBW29]
MTYNLEFDARALKEWRKLGDTVRQQLKKKLVEILTHPRIEANRLHGLPDCYKIKLRSSGYRLVYQVIDQEVMVFVVAVDK
RERDEVYRKATERLS

Download         Length: 288 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8963.34 Da        Isoelectric Point: 4.7962

>AT274023 WP_258348672.1 NZ_CP119366:4820210-4820449 [Pseudomonas sp. CBSPBW29]
MASINIRIDDDLKARAYHELEKLGVTPSELMRQALQYVAERGQLPFKPVLMTEDDEALLATVRERLAAPQRVKVSLDDL

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References